Evidence map›Paper›PMID 38250685›Full record

ArticleAnnals of gastroenterological surgery2024

Extracellular water to total body water ratio, a novel predictor of recurrence in patients with colorectal cancer.

Taichi Horino, Ryuma Tokunaga, Yuji Miyamoto, Takahiko Akiyama, Nobuya Daitoku, Yuki Sakamoto, Mayuko Ohuchi, Katsuhiro Ogawa, Naoya Yoshida, Hideo Baba

Open access · goldAbstract read
In one paragraph

Article in Annals of gastroenterological surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Taichi HorinoDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.ORCID https://orcid.org/0000-0003-1355-6772
Ryuma TokunagaDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.ORCID https://orcid.org/0000-0003-4326-0315
Yuji MiyamotoDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.
Takahiko AkiyamaDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.
Nobuya DaitokuDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.
Yuki SakamotoDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.
Mayuko OhuchiDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.
Katsuhiro OgawaDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.
Naoya YoshidaDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.ORCID https://orcid.org/0000-0002-8447-5278
Hideo BabaDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.ORCID https://orcid.org/0000-0002-3474-2550
Kumamoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Total body water (TBW) fraction, which accounts for 60% of body weight, is an important indicator of body composition, and the extracellular water to TBW ratio (ECW/TBW) is reportedly useful in predicting clinical outcomes of patients with organ disorders. We aimed to clarify the clinical impact of preoperative ECW/TBW status on survival outcomes in cancer patients. Methods: We used a database of 320 colorectal cancer (CRC) patients who underwent potentially curative resections. Preoperative ECW/TBW was measured using a bioelectrical impedance analysis (BIA), and its correlation with patient survival outcomes, clinicopathological factors, laboratory data, and comorbidities were analyzed. Results: A high preoperative ECW/TBW was significantly associated with poorer relapse-free survival (RFS; Conclusions: A high preoperative ECW/TBW was a predictive factor for recurrence and poorer overall survival independent of the tumor, node, and metastasis (TNM) stage. Our data suggest that preoperative evaluation of ECW/TBW using BIA might serve as a novel tool for developing CRC treatment strategies.

Indexed as

colorectal cancerextracellular waterintracellular waterprognosisrecurrence

Identifiers

PMID38250685
PMCPMC10797841
OpenAlexW4385706546

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.