Evidence map›Paper›PMID 38250678›Full record

ArticleAnnals of gastroenterological surgery2024

Trends in long-term outcomes of patients with HCV-associated hepatocellular carcinoma after hepatectomy: A comparison before and after introduction of direct-acting antivirus therapy.

Fumiaki Munekage, Tomoaki Yoh, Satoshi Ogiso, Takuya Kato, Nguyen Hai Nam, Kazuyuki Nagai, Yoichiro Uchida, Takashi Ito, Takamichi Ishii, Etsuro Hatano

Open access · goldAbstract read
In one paragraph

Article in Annals of gastroenterological surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Fumiaki MunekageDepartment of Surgery, Graduate School of Medicine Kyoto University Kyoto Japan.ORCID https://orcid.org/0009-0004-7325-8640
Tomoaki YohDepartment of Surgery, Graduate School of Medicine Kyoto University Kyoto Japan.ORCID https://orcid.org/0000-0001-6518-2077
Satoshi OgisoDepartment of Surgery, Graduate School of Medicine Kyoto University Kyoto Japan.ORCID https://orcid.org/0000-0002-9577-330X
Takuya KatoDepartment of Surgery, Graduate School of Medicine Kyoto University Kyoto Japan.
Nguyen Hai NamDepartment of Surgery, Graduate School of Medicine Kyoto University Kyoto Japan.
Kazuyuki NagaiDepartment of Surgery, Graduate School of Medicine Kyoto University Kyoto Japan.
Yoichiro UchidaDepartment of Surgery, Graduate School of Medicine Kyoto University Kyoto Japan.ORCID https://orcid.org/0000-0003-2266-7722
Takashi ItoDepartment of Surgery, Graduate School of Medicine Kyoto University Kyoto Japan.
Takamichi IshiiDepartment of Surgery, Graduate School of Medicine Kyoto University Kyoto Japan.
Etsuro HatanoDepartment of Surgery, Graduate School of Medicine Kyoto University Kyoto Japan.
Kyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Backgrounds: The success of direct-acting antiviral (DAA) therapy provides a cure for patients chronically infected with hepatitis C virus (HCV); however, outcomes after hepatectomy for HCV-associated hepatocellular carcinoma (HCC) before and after DAA introduction remain poorly studied. Methods: Patients who underwent R0/R1 hepatectomy for HCV-associated HCC were retrospectively analyzed. Two time periods were defined: Pre-DAA (2007-2011, December 2013 was defined as the end of follow-up) and Post-DAA groups (2014-2018, December 2020 was defined as the end of follow-up). Propensity score matching (PSM) analyses were performed to highlight the effect of DAA therapy. Results: A total of 155 patients with HCV-associated HCC were included in this study (Pre-DAA group, Conclusions: This study showed that survival outcomes were not changed in hepatectomized cases of HCV-associated HCC before and after the introduction of DAA therapy.

Indexed as

DAAdirect‐acting antiviralsHCCHCVhepatectomyhepatitis C virushepatocellular carcinomasurvival

Identifiers

PMID38250678
PMCPMC10797833
OpenAlexW4385635221

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.