Evidence map›Paper›PMID 38250599›Full record

ArticleFrontiers in neurorobotics2023

Intelligent digital tools for screening of brain connectivity and dementia risk estimation in people affected by mild cognitive impairment: the AI-Mind clinical study protocol.

Ira H Haraldsen, Christoffer Hatlestad-Hall, Camillo Marra, Hanna Renvall, Fernando Maestú, Jorge Acosta-Hernández, Soraya Alfonsin, Vebjørn Andersson, Abhilash Anand, Victor Ayllón and 59 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurorobotics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

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  6. Alpha rhythm and Alzheimer's disease: Has Hans Berger's dream come true?Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025
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  11. Health technology assessment framework for artificial intelligence-based technologies.International journal of technology assessment in health care · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

69 authors at 20 institutions in 8 countries.

Ira H HaraldsenDepartment of Neurology, Oslo University Hospital, Oslo, Norway.
Christoffer Hatlestad-HallDepartment of Neurology, Oslo University Hospital, Oslo, Norway.
Camillo MarraMemory Clinic, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Hanna RenvallDepartment of Neuroscience and Biomedical Engineering, Aalto University, Helsinki, Finland.
Fernando MaestúCentre for Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, Madrid, Spain.
Jorge Acosta-HernándezCenter for Computational Simulation, Universidad Politécnica de Madrid, Madrid, Spain.
Soraya AlfonsinCentre for Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, Madrid, Spain.
Vebjørn AnderssonDepartment of Neurology, Oslo University Hospital, Oslo, Norway.
Abhilash AnandPerformance and Assurance Solutions, Digital Solutions, DNV, Oslo, Norway.
Victor AyllónLurtis Rules S.L., Madrid, Spain.
Aleksandar BabicHealthcare Programme, Group Research and Development, DNV, Oslo, Norway.
Asma BelhadiDepartment of Computer Science, OsloMet-Oslo Metropolitan University, Oslo, Norway.
Cindy BirckAlzheimer Europe, Luxembourg, Luxembourg.
Ricardo BruñaCentre for Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, Madrid, Spain.
Naike CaragliaMemory Clinic, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Claudia CarrariniDepartment of Neuroscience and Neurorehabilitation, IRCCS San Raffaele, Rome, Italy.
Erik ChristensenPre Diagnostics AS, Oslo, Norway.
Americo CicchettiThe Graduate School of Health Economics and Management (ALTEMS), Catholic University of the Sacred Heart, Rome, Italy.
Signe DaugbjergThe Graduate School of Health Economics and Management (ALTEMS), Catholic University of the Sacred Heart, Rome, Italy.
Rossella Di BidinoThe Graduate School of Health Economics and Management (ALTEMS), Catholic University of the Sacred Heart, Rome, Italy.
Ana Diaz-PonceAlzheimer Europe, Luxembourg, Luxembourg.
Ainar DrewsIT Department, University of Oslo, Oslo, Norway.
Guido Maria GiuffrèMemory Clinic, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Jean GeorgesAlzheimer Europe, Luxembourg, Luxembourg.
Pedro Gil-GregorioDepartment of Geriatric Medicine, Hospital Universitario Clínico San Carlos, Madrid, Spain.
Dianne GoveAlzheimer Europe, Luxembourg, Luxembourg.
Tim M GoversDepartment of Medical Imaging, Radboud University Medical Center, Nijmegen, Netherlands.
Harry HallockHealthcare Programme, Group Research and Development, DNV, Oslo, Norway.
Marja HietanenDivision of Neuropsychology, HUS Neurocenter, Helsinki University Hospital and Helsinki University, Helsinki, Finland.
Lone HolmenDepartment of Neurology, Oslo University Hospital, Oslo, Norway.
Jaakko HottaDepartment of Neurology, Helsinki University Hospital and Clinical Neurosciences, Neurology, University of Helsinki, Helsinki, Finland.
Samuel KaskiDepartment of Computer Science, Helsinki Institute of Information Technology, Aalto University, Helsinki, Finland.
Rabindra KhadkaDepartment of Computer Science, OsloMet-Oslo Metropolitan University, Oslo, Norway.
Antti S KinnunenBioMag Laboratory, HUS Medical Imaging Centre, Helsinki University Hospital, Helsinki University and Aalto University School of Science, Helsinki, Finland.
Anne M KoivistoDepartment of Neurology, Helsinki University Hospital and Clinical Neurosciences, Neurology, University of Helsinki, Helsinki, Finland.
Shrikanth KulashekharBioMag Laboratory, HUS Medical Imaging Centre, Helsinki University Hospital, Helsinki University and Aalto University School of Science, Helsinki, Finland.
Denis LarsenDepartment of Computer Science, OsloMet-Oslo Metropolitan University, Oslo, Norway.
Mia LiljeströmDepartment of Neuroscience and Biomedical Engineering, Aalto University, Helsinki, Finland.
Pedro G LindDepartment of Computer Science, OsloMet-Oslo Metropolitan University, Oslo, Norway.
Alberto Marcos DoladoInstitute of Sanitary Investigation (IdISSC), San Carlos University Hospital, Madrid, Spain.
Serena MarshallHealthcare Programme, Group Research and Development, DNV, Oslo, Norway.
Susanne MerzDepartment of Neuroscience and Biomedical Engineering, Aalto University, Helsinki, Finland.
Francesca MiragliaDepartment of Neuroscience and Neurorehabilitation, IRCCS San Raffaele, Rome, Italy.
Juha MontonenBioMag Laboratory, HUS Medical Imaging Centre, Helsinki University Hospital, Helsinki University and Aalto University School of Science, Helsinki, Finland.
Ville MäntynenBioMag Laboratory, HUS Medical Imaging Centre, Helsinki University Hospital, Helsinki University and Aalto University School of Science, Helsinki, Finland.
Anne Rita ØksengårdThe Norwegian Health Association, Oslo, Norway.
Javier OlazaránNeurology Service, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Teemu PaajanenFinnish Institute of Occupational Health, Helsinki, Finland.
José M PeñaLurtis Rules S.L., Madrid, Spain.
Luis PeñaLurtis Rules S.L., Madrid, Spain.
Daniel Lrabien PenicheSchool of Digital Technologies, Tallinn University, Tallinn, Estonia.
Ana S PerezDepartment of Neurology, Oslo University Hospital, Oslo, Norway.
Mohamed RadwanDepartment of Computer Science, OsloMet-Oslo Metropolitan University, Oslo, Norway.
Federico Ramírez-TorañoCentre for Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, Madrid, Spain.
Andrea Rodríguez-PedreroCentre for Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, Madrid, Spain.
Timo SaarinenBioMag Laboratory, HUS Medical Imaging Centre, Helsinki University Hospital, Helsinki University and Aalto University School of Science, Helsinki, Finland.
Mario Salas-CarrilloInstitute of Sanitary Investigation (IdISSC), San Carlos University Hospital, Madrid, Spain.
Riitta SalmelinDepartment of Neuroscience and Biomedical Engineering, Aalto University, Helsinki, Finland.
Sonia SousaSchool of Digital Technologies, Tallinn University, Tallinn, Estonia.
Abdillah SuyuthiPerformance and Assurance Solutions, Digital Solutions, DNV, Oslo, Norway.
Mathias ToftDepartment of Neurology, Oslo University Hospital, Oslo, Norway.
Pablo TohariaCenter for Computational Simulation, Universidad Politécnica de Madrid, Madrid, Spain.
Thomas TveitstølDepartment of Neurology, Oslo University Hospital, Oslo, Norway.
Mats TveterDepartment of Neurology, Oslo University Hospital, Oslo, Norway.
Ramesh UpretiDepartment of Neurology, Oslo University Hospital, Oslo, Norway.
Robin J VermeulenDepartment of Medical Imaging, Radboud University Medical Center, Nijmegen, Netherlands.
Fabrizio VecchioDepartment of Neuroscience and Neurorehabilitation, IRCCS San Raffaele, Rome, Italy.
Anis YazidiDepartment of Computer Science, OsloMet-Oslo Metropolitan University, Oslo, Norway.
Paolo Maria RossiniDepartment of Neuroscience and Neurorehabilitation, IRCCS San Raffaele, Rome, Italy.
Oslo University Hospital · NOAalto University · FIOsloMet – Oslo Metropolitan University · NOUniversidad Complutense de Madrid · ESAlzheimer Europe · LUAgostino Gemelli University Polyclinic · ITDNV (Norway) · NOIstituto di Ricovero e Cura a Carattere Scientifico San RaffaeleLight Prescriptions Innovators (Spain) · ESUniversità Cattolica del Sacro Cuore · ITUniversity of Helsinki · FIHelsinki University Hospital · FIInstituto de Investigación Sanitaria del Hospital Clínico San Carlos · ESRadboud University Medical Center · NLTallinn University · EEUniversidad Politécnica de Madrid · ESFinnish Institute of Occupational Health · FIHelsinki Institute for Information Technology · FIHospital Clínico San Carlos · ESHospital General Universitario Gregorio Marañón · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

More than 10 million Europeans show signs of mild cognitive impairment (MCI), a transitional stage between normal brain aging and dementia stage memory disorder. The path MCI takes can be divergent; while some maintain stability or even revert to cognitive norms, alarmingly, up to half of the cases progress to dementia within 5 years. Current diagnostic practice lacks the necessary screening tools to identify those at risk of progression. The European patient experience often involves a long journey from the initial signs of MCI to the eventual diagnosis of dementia. The trajectory is far from ideal. Here, we introduce the AI-Mind project, a pioneering initiative with an innovative approach to early risk assessment through the implementation of advanced artificial intelligence (AI) on multimodal data. The cutting-edge AI-based tools developed in the project aim not only to accelerate the diagnostic process but also to deliver highly accurate predictions regarding an individual's risk of developing dementia when prevention and intervention may still be possible. AI-Mind is a European Research and Innovation Action (RIA H2020-SC1-BHC-06-2020, No. 964220) financed between 2021 and 2026. First, the AI-Mind

Indexed as

AI-Mindartificial intelligenceclinical study protocoldementiaelectroencephalography (EEG)machine learningmagnetoencephalography (MEG)mild cognitive impairment

Identifiers

PMID38250599
PMCPMC10796757
OpenAlexW4390610239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.