Evidence map›Paper›PMID 38250545›Full record

ArticleJournal of 3D printing in medicine2023

3D-bioprinted cardiac tissues and their potential for disease modeling.

Milena Restan Perez, Victor Alisson da Silva, Polette Esmeralda Cortez, Binata Joddar, Stephanie Michelle Willerth

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of 3D printing in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Milena Restan PerezAxolotl Biosciences, 3800 Finnerty Road, Victoria, BC, V8W 2Y2, Canada.
Victor Alisson da SilvaDepartment of Mechanical Engineering, University of Victoria, 3800 Finnerty Road, Victoria, BC, V8W 2Y2, Canada.
Polette Esmeralda CortezDepartment of Metallurgical, Materials & Biomedical Engineering, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968, USA.
Binata JoddarDepartment of Metallurgical, Materials & Biomedical Engineering, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968, USA.
Stephanie Michelle WillerthAxolotl Biosciences, 3800 Finnerty Road, Victoria, BC, V8W 2Y2, Canada.

Funding

Development and validation of a novel bioprinted, human-diabetic cardiac organoid modelSC1HL154511 · NHLBI · UNIVERSITY OF TEXAS EL PASO · PI HAN, KYUNG-AN · 2020 to 2023
$1.2M
NHLBI NIH HHS SC1 HL154511
6 · The paper itself

Abstract

Heart diseases cause over 17.9 million total deaths globally, making them the leading source of mortality. The aim of this review is to describe the characteristic mechanical, chemical and cellular properties of human cardiac tissue and how these properties can be mimicked in 3D bioprinted tissues. Furthermore, the authors review how current healthy cardiac models are being 3D bioprinted using extrusion-, laser- and inkjet-based printers. The review then discusses the pathologies of cardiac diseases and how bioprinting could be used to fabricate models to study these diseases and potentially find new drug targets for such diseases. Finally, the challenges and future directions of cardiac disease modeling using 3D bioprinting techniques are explored.

Indexed as

bioprintingcardiac tissuescardiomyocytesdisease modellingreviewstem cells

Identifiers

PMID38250545
PMCPMC10798787

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.