Evidence map›Paper›PMID 38250533›Full record

ArticleBioinformation2023

Effect of curcumin, betadine and chlorhexidine in gingival wound healing.

Ankita Agrawal, Ekka Rashmi Kiran, Singla Deepika, Patiksha Kumar, Deepak Kochar, Sidhu Ruhi, Bharat Gupta, Kapil Paiwal

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ankita AgrawalDepartment of Conservative and Endodontics, Buddha Institute of Dental Sciences and Hospital, Patna, Bihar, India.
Ekka Rashmi KiranDepartment of Oral Medicine and Radiology, Bhabha College of Dental Sciences, Bhopal, MP, India.
Singla DeepikaDepartment of Conservative Dentistry & Endodontics, Desh Bhagat Dental College & Hospital, Mandi Gobindgarh, Punjab, India.
Patiksha KumarDepartment of Oral Pathology & Microbiology, Government College of Dentistry, Indore, M.P., India.
Deepak KocharDepartment of Periodontology, M.M. College of Dental Sciences & Research, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, India.
Sidhu RuhiOral Medicine and Radiology, MNDAV Dental College and Hospital, Tatul, Oachghat, Solan, Himachal Pradesh, India.
Bharat GuptaDepartment of Periodontics, MGM Dental College, Navi Mumbai, India.
Kapil PaiwalDepartment of Oral & Maxillofacial Pathology, Daswani Dental College & Research Center, Kota, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of chlorhexidine (CHX) digluconate, Betadine (BET), curcumin (CUR) on gingival wound healing is of interest to dental practitioners. Hence, we studied the average fibroblast viability % for each of the concentrations of CUR, BET and CHX over various time durations. It was found that mean percentage of viability of fibroblasts is high in CUR and low in CHX at all time periods while the mean percentage of viability of fibroblasts in BET 1% was greater than CHX but lower than CUR at all time periods. Thus, curcumin at a concentration of 0.003% demonstrates the least cytotoxicity for fibroblasts. Hence, it is the most effective bacterial suppression, and the best wound healing.

Indexed as

chlorhexidineCurcuminhuman fibroblast viabilitymigration

Identifiers

PMID38250533
PMCPMC10794752

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.