Evidence map›Paper›PMID 38250386›Full record

ArticleACS omega2024

Apolipoprotein E3 Containing Nanodiscs as Vehicles for Transport and Targeted Delivery of Flavonoid Luteolin.

Vernon Gil Laylo Benedicto, Zahraa Haguar, Abbas Abdulhasan, Vasanthy Narayanaswami

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Vernon Gil Laylo BenedictoDepartment of Chemistry and Biochemistry, California State University, Long Beach, 1250 Bellflower Boulevard, Long Beach, California 90840, United States.ORCID https://orcid.org/0000-0002-0257-8303
Zahraa HaguarDepartment of Chemistry and Biochemistry, California State University, Long Beach, 1250 Bellflower Boulevard, Long Beach, California 90840, United States.
Abbas AbdulhasanDepartment of Chemistry and Biochemistry, California State University, Long Beach, 1250 Bellflower Boulevard, Long Beach, California 90840, United States.
Vasanthy NarayanaswamiDepartment of Chemistry and Biochemistry, California State University, Long Beach, 1250 Bellflower Boulevard, Long Beach, California 90840, United States.ORCID https://orcid.org/0000-0001-7088-4057
California State University, Long Beach · US

Funding

Research Initiative for Scientific Enhancement at CSULBR25GM071638 · NIGMS · CALIFORNIA STATE UNIVERSITY LONG BEACH · PI BUONORA, PAUL T, FRASER, DEBORAH ANN · 2004 to 2022
$10.0M
Transendothelial transport mediated modulations to the High Density LipoproteinSC3GM105561 · NIGMS · CALIFORNIA STATE UNIVERSITY LONG BEACH · PI NARAYANASWAMI, VASANTHY · 2013 to 2021
$876k
Role Of Apolipoprotein E In Maintaining the Blood Brain Barrier IntegrityR16NS140312 · NINDS · CALIFORNIA STATE UNIVERSITY LONG BEACH · PI VASANTHY NARAYANASWAMI · 2024 to 2026
$443k
NIGMS NIH HHS R25 GM071638NIGMS NIH HHS SC3 GM105561NINDS NIH HHS R16 NS140312
6 · The paper itself

Abstract

Luteolin is a flavonoid that possesses multiple beneficial biological properties, such as anticancer, antioxidant, and anti-inflammatory effects. The objective of this study is to test the hypothesis that luteolin can be transported across a cell via a nanodisc delivery system and delivered to intracellular sites. Luteolin was incorporated into reconstituted high-density lipoprotein complexes made up of apolipoprotein E3 (apoE3) N-terminal domain (apoE3NT) and 1,2-dimystrioyl-

Identifiers

PMID38250386
PMCPMC10795050
OpenAlexW4390563488

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.