ArticleACS omega2024
Colorimetric Detection of Furfural with Enhanced Visible Absorption of Furfural-DNPH in Basic Conditions.
Article in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 6 citations in OpenAlex.
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Furfural is an intermediary toxic aldehyde compound produced during heat-induced food processing and storage. Furfural is also formed by the degradation of cellulosic insulation in oil-immersed electric potential transformers, whose level is an important indicator of aging for replacement. In this study, we report a new means to detect the trace level of furfural in a colorimetric manner. Furfural is reacted with dinitrophenylhydrazine (DNPH) in acid solutions. The colorless furfural-DNPH compound turns orange-colored as the solution changes to basic. The delocalization of the π-electron in the DNPH-aldehyde derivatives at the basic condition causes the shift of the absorption peak from 318 to 470 nm, which renders the solution orange-colored. The color and absorbance are saturated in 20 min of incubation. There is high linearity between the absorbance and the concentration of furfural in the range of 0-0.2 mM, which enables the quantitative detection of furfural. The limit of detection is estimated to be as low as 1.76 μM for the absorbance analysis and 10 μM for the naked eyes. The colorimetric assay protocol is applicable to the detection of various aromatic aldehydes, which show strong π-electron delocalization and is not applicable to aliphatic aldehydes due to lack of delocalization. This simple assay can be conducted in typical 96-well microplates using a microplate reader, which provides a low-cost and high-throughput screening. Therefore, we believe that our method is potentially applicable for the quantitative detection of aromatic aldehydes in various samples from foods, electronic devices, and so on.
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Registered trials
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