ArticleCritical care explorations2024
Improving Outcomes in Mechanically Ventilated Adult ICU Patients Following Implementation of the ICU Liberation (ABCDEF) Bundle Across a Large Healthcare System.
Article in Critical care explorations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Risk assessment and prevention of postoperative and postprocedural respiratory failure: recommendations from an international expert panel.British journal of anaesthesia · 2026Guideline
- Five-decade prevalence of delirium in pneumonia, risk factors and associated mortality: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Medication Appropriateness and Potentially Inappropriate Medications in Older Critical Care Patients: A Scoping Review.Drugs & aging · 2026Review
- Effectiveness of Non-Pharmacological Interventions for the Prevention of Postoperative Delirium in Critically Ill Adult Patients: A Systematic Review and Meta-Analysis.Nursing reports (Pavia, Italy) · 2026Review
- Critical care delirium: prevention, identification and management: a narrative review.Anaesthesia · 2026Review
- Characteristics and Reported Practices of ICUs Participating in the Sedation, Analgesia and Delirium Management International Study: Variability in Site-Level Management of Mechanically Ventilated Patients.Critical care explorations · 2026Article
- Minimum observation time to determine ventilator liberation success and its associated factors in tracheostomized patients in intensive and high-care units in Japan: a single-center retrospective study.Acute and critical care · 2026Article
- Barriers and Facilitators to ICU Liberation Bundle Implementation and Compliance.Critical care explorations · 2026Article
- [Advanced nursing practice in intensive care units : Implementation and further development].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026Review
- Sedation practices and associated clinical outcomes among adult ICU patients managed by advanced practice providers versus resident physicians.Journal of critical care · 2026Article
- Enhancing nurses' competence in mechanical ventilation: a quasi-experimental study and its association with patient severity using APACHE II.Frontiers in medicine · 2026Article
- VV-ECMO-supported management of severe ARDS secondary to melioidosis sepsis: A case report and concise review.IDCases · 2026Article
- From Resuscitation to Rehabilitation: The Post-Intensive Care Syndrome Continuum in Sepsis Care.Journal of clinical medicine · 2025Review
- Unveiling the conceptual and intellectual map of care bundle research in ICUs: Trends, key issues, and collaborative networks.Nursing in critical care · 2025Article
- Effect of educational program on nurses' performance regarding application of liberation bundle in pediatric intensive care unit.BMC nursing · 2025Article
- The implementation gap in critical care: From nutrition to ventilation.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025Article
- From the Intensive Care Unit to Recovery: Managing Post-intensive Care Syndrome in Critically Ill Patients.Cureus · 2024Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo measure how the ICU Liberation Bundle (aka ABCDEF Bundle or the Bundle) affected clinical outcomes in mechanically ventilated (MV) adult ICU patients, as well as bundle sustainability and spread across a healthcare system.
designWe conducted a multicenter, prospective, cohort observational study to measure bundle performance versus patient outcomes and sustainability in 11 adult ICUs at six community hospitals. We then prospectively measured bundle spread and performance across the other 28 hospitals of the healthcare system.
settingA large community-based healthcare system. PATIENTS: In 11 study ICUs, we enrolled 1,914 MV patients (baseline
interventionsWe used evidence-based strategies to implement the bundle in all 34 hospitals. MEASUREMENTS AND MAIN
resultsWe compared outcomes for the 12-month baseline and bundle performance periods. Bundle implementation reduced ICU length of stay (LOS) by 0.5 days (
conclusionsThe ICU Liberation Bundle improves outcomes in MV adult ICU patients. Evidence-based implementation strategies improve bundle performance, spread, and sustainability across large healthcare systems.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.