Evidence map›Paper›PMID 38250201›Full record

ArticleOpen forum infectious diseases2024

Outbreak of Diarrhea Caused by a Novel

Romeo Toriro, Scott Pallett, Stephen Woolley, Charlie Bennett, Isra Hale, Jennifer Heylings, Daniel Wilkins, Thomas Connelly, Kennedy Muia, Patrick Avery and 12 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. A review of recentCurrent research in parasitology & vector-borne diseases · 2025
    Review
  6. Review
  7. Deciphering a cryptic minefield: A guide toCurrent research in parasitology & vector-borne diseases · 2025
    Review
  8. Article
  9. Genetic diversity ofCurrent research in parasitology & vector-borne diseases · 2025
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Romeo ToriroArmy Medical Services, Robertson House, Royal Military Academy Sandhurst, Camberley, Surrey, UK.ORCID https://orcid.org/0000-0001-5984-5276
Scott PallettCentre of Defence Pathology, Royal Centre for Defence Medicine, Queen Elizabeth Hospital Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0002-9465-5299
Stephen WoolleyDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, Merseyside, UK.
Charlie BennettCentre of Defence Pathology, Royal Centre for Defence Medicine, Queen Elizabeth Hospital Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0002-9385-8975
Isra Hale3 Medical Regiment, Fulwood Barracks, Preston, Lancashire, UK.
Jennifer Heylings28 (C-CBRN) Engineer Regiment, Rock Barracks, Woodbridge, Suffolk, UK.
Daniel Wilkins2nd Battalion the Rifles, Thiepval Barracks, Lisburn, UK.ORCID https://orcid.org/0000-0001-5150-4610
Thomas Connelly29 Public Health Division Medical Group, HQ 3 (UK) Division, Bulford, Wiltshire, UK.
Kennedy MuiaBritish Army Training Unit (Kenya), Nanyuki, Kenya.
Patrick AveryDefence Primary Healthcare, Medical Centre, Nanyuki, Kenya.
Andrew StuartDefence Primary Healthcare, Medical Centre, Nanyuki, Kenya.
Laura MorganHQ 1st (UK) Division, Imphal Barracks, York, Yorkshire, UK.
Mark DaviesBritish Army Training Unit (Kenya), Nanyuki, Kenya.
William NevinDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, Merseyside, UK.
Oliver QuantickArmy Health, Army Headquarters, Andover, Hampshire, UK.
Guy RobinsonCryptosporidium  Reference Unit, Public Health Wales Microbiology, Singleton Hospital, Sketty, Swansea, Wales, UK.
Kristin ElwinCryptosporidium  Reference Unit, Public Health Wales Microbiology, Singleton Hospital, Sketty, Swansea, Wales, UK.
Rachel ChalmersCryptosporidium  Reference Unit, Public Health Wales Microbiology, Singleton Hospital, Sketty, Swansea, Wales, UK.
Daniel BurnsRoyal Centre for Defence Medicine, Birmingham, UK.
Nicholas BeechingDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, Merseyside, UK.ORCID https://orcid.org/0000-0002-7019-8791
Thomas FletcherDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, Merseyside, UK.
Matthew O'SheaCentre of Defence Pathology, Royal Centre for Defence Medicine, Queen Elizabeth Hospital Birmingham, Birmingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We report clinical, epidemiological, and laboratory features of a large diarrhea outbreak caused by a novel Methods: Data were collated from diarrhea cases, and fecal samples were analyzed on site using the multiplex polymerase chain reaction (PCR) BioFire FilmArray. Water was tested using Colilert kits (IDEXX, UK). DNA was extracted from feces for molecular characterization of Results: One hundred seventy-two of 1200 (14.3%) personnel at risk developed diarrhea over 69 days. One hundred six primary fecal samples were tested, and 63/106 (59.4%; 95% CI, 0.49%-0.69%) were positive for Conclusions: Real-time multiplex PCR fecal testing was vital in managing this large cryptosporidiosis outbreak. The etiology of a rare

Indexed as

CryptosporidiumdiarrheaDNA extraction and speciationmilitary populationoutbreak

Identifiers

PMID38250201
PMCPMC10798851

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.