Evidence map›Paper›PMID 38250171›Full record

ArticleAnnual reviews in control2022

Developing control-theoretic objectives for large-scale brain dynamics and cognitive enhancement.

Matthew F Singh, Michael W Cole, Todd S Braver, ShiNung Ching

Abstract read
In one paragraph

Article in Annual reviews in control, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew F SinghElectrical and Systems Engineering, Washington University in St. Louis, St. Louis, 63130, MO, USA.
Michael W ColeCenter for Molecular and Behavioral Neuroscience, Rutgers University, Newark, 07102, NJ, USA.
Todd S BraverPsychological and Brain Science, Washington University in St. Louis, St. Louis, 63130, MO, USA.
ShiNung ChingElectrical and Systems Engineering, Washington University in St. Louis, St. Louis, 63130, MO, USA.

Funding

BIOMEDICAL RESEARCH TRAINING IN DRUG ABUSET32DA007261 · NIDA · WASHINGTON UNIVERSITY · PI ARPANA AGRAWAL, Jose A Moron-Concepcion · 1991 to 2026
$8.8M
Dual Mechanisms of Cognitive ControlR37MH066078 · NIMH · WASHINGTON UNIVERSITY · PI BRAVER, TODD S · 2013 to 2022
$7.2M
DUAL MECHANISMS OF COGNITIVE CONTROLR01MH066078 · NIMH · WASHINGTON UNIVERSITY · PI BRAVER, TODD S · 2002 to 2012
$3.3M
Cognitive enhancement through model-based and individualized neurostimulationR21MH132240 · NIMH · WASHINGTON UNIVERSITY · PI BRAVER, TODD S, CHING, SHINUNG · 2023 to 2024
$429k
Dual Mechanisms of Cognitive ControlR56MH066078 · NIMH · WASHINGTON UNIVERSITY · PI BRAVER, TODD S · 2007 to 2007
$342k
NIDA NIH HHS T32 DA007261NIMH NIH HHS R01 MH066078NIMH NIH HHS R21 MH132240NIMH NIH HHS R37 MH066078NIMH NIH HHS R56 MH066078
6 · The paper itself

Abstract

The development of technologies for brain stimulation provides a means for scientists and clinicians to directly actuate the brain and nervous system. Brain stimulation has shown intriguing potential in terms of modifying particular symptom clusters in patients and behavioral characteristics of subjects. The stage is thus set for optimization of these techniques and the pursuit of more nuanced stimulation objectives, including the modification of complex cognitive functions such as memory and attention. Control theory and engineering will play a key role in the development of these methods, guiding computational and algorithmic strategies for stimulation. In particular, realizing this goal will require new development of frameworks that allow for controlling not only brain activity, but also latent dynamics that underlie neural computation and information processing. In the current opinion, we review recent progress in brain stimulation and outline challenges and potential research pathways associated with exogenous control of cognitive function.

Indexed as

Brain dynamicsBrain stimulationNeural reachabilityNeurocontrol theory

Identifiers

PMID38250171
PMCPMC10798814

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.