Evidence map›Paper›PMID 38250159›Full record

ArticleInternational journal of biological sciences2024

IGF2BP2 promotes cell invasion and epithelial-mesenchymal transition through Src-mediated upregulation of EREG in oral cancer.

Chiao-Wen Lin, Wei-En Yang, Chun-Wen Su, Hsueh-Ju Lu, Shih-Chi Su, Shun-Fa Yang

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Impact ofInternational journal of medical sciences · 2026
    Article
  3. Article
  4. Association ofInternational journal of medical sciences · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. IGF2BP2: an mCellular & molecular biology letters · 2025
    Review
  9. Article
  10. IMPlications of IMP2 in RNA Biology and Disease.International journal of molecular sciences · 2025
    Review
  11. Review
  12. International journal of medical sciences · 2025
    Article
  13. Article
  14. The Impact ofJournal of Cancer · 2025
    Article
  15. Genetic variants ofInternational journal of medical sciences · 2025
    Article
  16. Article
  17. Article
  18. The mRecent patents on anti-cancer drug discovery · 2025
    Article
  19. Review
  20. NInternational journal of biological sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Chiao-Wen LinInstitute of Oral Sciences, Chung Shan Medical University, Taichung, Taiwan.
Wei-En YangInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Chun-Wen SuInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Hsueh-Ju LuDivision of Hematology and Oncology, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.
Shih-Chi SuWhole-Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital, Keelung, Taiwan.
Shun-Fa YangInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Chung Shan Medical University · TWChang Gung Memorial Hospital · TWChung Shan Medical University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2), with high affinity to a myriad of RNA transcripts, has been shown to elicit promotive effects on tumorigenesis and metastasis. Yet, the functional involvement of IGF2BP2 in the progression of oral squamous cell carcinoma (OSCC) remains poorly understood. In this study, we showed that IGF2BP2 was upregulated in head and neck cancer, and high levels of IGF2BP2 were associated with poor survival. In

Indexed as

Mouth NeoplasmsRNA-Binding ProteinsSquamous Cell Carcinoma of Head and NeckEpiregulinEpithelial-Mesenchymal TransitionHumansUp-RegulationEpiregulinEREG protein, humanIGF2BP2 protein, humanRNA-Binding Proteinsepithelia-mesenchymal transitioninsulin-like growth factor 2 mRNA binding protein 2oral squamous cell carcinoma

Identifiers

PMID38250159
PMCPMC10797698
OpenAlexW4390485151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.