Evidence map›Paper›PMID 38250042›Full record

ArticleTheranostics2024

Integrated analysis of single-cell and bulk transcriptomics develops a robust neuroendocrine cell-intrinsic signature to predict prostate cancer progression.

Tingting Zhang, Faming Zhao, Yahang Lin, Mingsheng Liu, Hongqing Zhou, Fengzhen Cui, Yang Jin, Liang Chen, Xia Sheng

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Theranostics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Identification of Epigenetic Regulator-Associated Genes in Keloid Disease Through Integrated Bulk and Single-Cell Transcriptomics With RT-qPCR Validation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
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  16. Neuroendocrine prostate cancer (NEPC)-associatedCancer pathogenesis and therapy · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Tingting ZhangKey Laboratory of Environmental Health, Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Faming ZhaoKey Laboratory of Environmental Health, Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yahang LinDepartment of Neurology, Wuhan Fourth Hospital/Pu'ai Hospital, Wuhan, China.
Mingsheng LiuThe Second Ward of Urology, Qujing Affiliated Hospital of Kunming Medical University, Qujing, China.
Hongqing ZhouThe Second Ward of Urology, Qujing Affiliated Hospital of Kunming Medical University, Qujing, China.
Fengzhen CuiKey Laboratory of Environmental Health, Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yang JinInstitute for Cancer Genetics and Informatics, Oslo University Hospital, Oslo, Norway.
Liang ChenDepartment of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xia ShengKey Laboratory of Environmental Health, Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Huazhong University of Science and Technology · CNKunming Medical University · CNHainan University · CNOslo University Hospital · NOWuhan Puai Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroendocrine prostate cancer (NEPC) typically implies severe lethality and limited treatment options. The precise identification of NEPC cells holds paramount significance for both research and clinical applications, yet valid NEPC biomarker remains to be defined.

Indexed as

Neuroendocrine CellsProstatic NeoplasmsGene Expression ProfilingHumansMaleProstateTranscriptomebiomarkercomputational biology and bioinformaticsmachine learningneuroendocrine prostate cancersingle-cell

Identifiers

PMID38250042
PMCPMC10797290
OpenAlexW4390700107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.