Molecular Insights into the Breast and Prostate Cancer Cells in Response to the Change of Extracellular Zinc.

Shital K Barman, Monokesh K Sen, David A Mahns, Ming J Wu, Chandra S Malladi

Open access · hybridAbstract read

In one paragraph

Article in Journal of oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.3field-weighted citation impact, top 49% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shital K BarmanSchool of Science, Western Sydney University, Locked Bag 1797, Penrith, NSW 2751, Australia.ORCID https://orcid.org/0000-0002-9855-8242

Monokesh K SenCharles Perkins Centre, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown 2006, NSW, Australia.ORCID https://orcid.org/0000-0003-3988-9196

David A MahnsSchool of Medicine, Western Sydney University, Locked Bag 1797, Penrith, NSW 2751, Australia.ORCID https://orcid.org/0000-0003-2131-9638

Ming J WuSchool of Science, Western Sydney University, Locked Bag 1797, Penrith, NSW 2751, Australia.ORCID https://orcid.org/0000-0003-0577-1907

Chandra S MalladiProteomics and Lipidomics Lab, School of Medicine, Western Sydney University, Locked Bag 1797, Penrith, NSW 2751, Australia.ORCID https://orcid.org/0000-0002-5882-8228

Western Sydney University · AUThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zinc dyshomeostasis is manifested in breast and prostate cancer cells. This study attempted to uncover the molecular details prodded by the change of extracellular zinc by employing a panel of normal and cancerous breast and prostate cell lines coupled with the top-down proteomics with two-dimensional gel electrophoresis followed by liquid chromatography-tandem mass spectrometry. The protein samples were generated from MCF-7 breast cancer cells, MCF10A normal breast cells, PC3 prostate cancer cells, and RWPE-1 normal prostate cells with or without exogenous zinc exposure in a time course (

Identifiers

PMID38249992

DOI10.1155/2024/9925970

PMCPMC10798840

OpenAlexW4390787643

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.