Evidence map›Paper›PMID 38249962›Full record

ArticleFrontiers in medicine2023

Differences in the detection of circulating Hsp90 alpha between patients with atopic dermatitis and dermatitis herpetiformis.

Krzysztof Sitko, Sarolta Kárpáti, Grzegorz Węgrzyn, Grzegorz Mincewicz, Magdalena Trzeciak, Michael Kasperkiewicz, Stefan Tukaj

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Krzysztof SitkoDepartment of Molecular Biology, Faculty of Biology, University of Gdańsk, Gdańsk, Poland.
Sarolta KárpátiDepartment of Dermatology, Venereology and Dermatooncology, Semmelweis University, Budapest, Hungary.
Grzegorz WęgrzynDepartment of Molecular Biology, Faculty of Biology, University of Gdańsk, Gdańsk, Poland.
Grzegorz MincewiczDepartment of Molecular Biology, Faculty of Biology, University of Gdańsk, Gdańsk, Poland.
Magdalena TrzeciakDepartment of Dermatology, Venereology and Allergology, Medical University of Gdańsk, Gdańsk, Poland.
Michael KasperkiewiczDepartment of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Stefan TukajDepartment of Molecular Biology, Faculty of Biology, University of Gdańsk, Gdańsk, Poland.
University of Gdańsk · PLGdańsk Medical University · PLSemmelweis University · HUUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heat shock protein 90 alpha (Hsp90α) is one of the key intra- and extracellular chaperones responsible for the biological activity of various signaling molecules that are involved in (auto)immune-mediated inflammatory diseases. Recent epidemiologic data suggest that patients with atopic dermatitis (AD) are at risk for several autoimmune diseases, including dermatitis herpetiformis (DH), an extraintestinal manifestation of celiac disease (CD). In addition, pruritic diseases such as AD may be confused clinically with DH. In this study, we aimed to determine the role of circulating Hsp90α in patients with AD in relation to patients with DH, CD, and healthy controls. Using an enzyme-linked immunosorbent assay, levels of circulating Hsp90α were determined in serum samples derived from patients with AD (

Indexed as

atopic dermatitis (AD)autoimmune diseasesCOVID-19dermatitis herpetiformis (DH)heat shock protein 90 (Hsp90)

Identifiers

PMID38249962
PMCPMC10796992
OpenAlexW4390611609

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.