Evidence map›Paper›PMID 38249946›Full record

ReviewSAGE open medicine2024

Insights into craniosynostosis management in low- and middle-income countries: A narrative review of outcomes, shortcomings and paediatric neurosurgery capacity.

Andrew Awuah Wireko, Arjun Ahluwalia, Syed Hasham Ali, Muhammad Hamza Shah, Nicholas Aderinto, Sumitaksha Banerjee, Sakshi Roy, Tomas Ferreira, Joecelyn Kirani Tan, Christin Berjaoui and 6 more

Abstract readReview
In one paragraph

Review in SAGE open medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Neurodevelopmental outcomes in children with craniosynostosis: a retrospective cross-sectional analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  2. Non-syndromic craniosynostosis.Nature reviews. Disease primers · 2025
    Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Andrew Awuah WirekoFaculty of Medicine, Sumy State University, Sumy, Ukraine.ORCID https://orcid.org/0000-0003-2380-2949
Arjun AhluwaliaSchool of Medicine, Queen's University Belfast, Belfast, UK.
Syed Hasham AliFaculty of Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Muhammad Hamza ShahSchool of Medicine, Queen's University Belfast, Belfast, UK.
Nicholas AderintoInternal Medicine Department, Lautech Teaching Hospital, Ogbomosho, Nigeria.
Sumitaksha BanerjeeBurdwan Medical College and Hospital, Barddhaman, West Bengal, India.
Sakshi RoySchool of Medicine, Queen's University Belfast, Belfast, UK.
Tomas FerreiraDepartment of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Joecelyn Kirani TanFaculty of Medicine, University of St Andrews, St. Andrews, Scotland, UK.
Christin BerjaouiFaculty of Medicine, Beirut Arab University, Beirut, Lebanon.
Saibaba GuggilapuFaculty of Medicine, Bangalore Medical College and Research Institute, Bangalore, India.
Louisa Sowah QuarshieNorwich Medical School, University of East Anglia, Norwich, UK.
Hareesha Rishab BharadwajFaculty of Biology Medicine and Health, The University of Manchester, Manchester, UK.
Favour Tope AdebusoyeFaculty of Medicine, Sumy State University, Sumy, Ukraine.ORCID https://orcid.org/0000-0001-5362-3920
Toufik Abdul-RahmanFaculty of Medicine, Sumy State University, Sumy, Ukraine.
Oday AtallahDepartment of Neurosurgery, Hannover Medical School, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Craniosynostosis, marked by premature cranial suture fusion, necessitates prompt intervention to avert developmental, neurological, and aesthetic issues. While high-income countries have advanced in managing this condition, low- and middle-income countries grapple with substantial healthcare access disparities. This narrative review explores current craniosynostosis management in low- and middle-income countries. The review focused on studies published between 2008 and 2023. The focus was neurosurgical outcomes, and the search utilised databases like PubMed, EMBASE, Google Scholar, the Cochrane Library and Scopus, incorporating specific keywords and phrases. An in-depth analysis of 21 included studies reveals noteworthy positive outcomes, including low mortality, successful corrections and sustained efficacy. These advancements stem from enhanced pre-operative strategies, surgical techniques and postoperative care. Nonetheless, challenges persist, encompassing complications, mortality, reoperations, and treatment disparities, particularly in low- and middle-income countries constrained by financial and expertise limitations. The enhancement of clinical practice and the formulation of effective policies in the future entail several key strategies. These include the reinforcement of specialised healthcare infrastructure and diagnostic capabilities, the ongoing training and retention of neurosurgeons, the improvement of funding mechanisms, and the promotion of equitable access. Additionally, a crucial focus is placed on fortifying paediatric neurosurgical care in low- and middle-income countries. The recommendations underscore the importance of collaborative initiatives, the development of specialised healthcare infrastructure, and the implementation of strategic policies to not only advance pediatric neurosurgical care but also to address existing gaps in management.

Indexed as

congenital abnormalitiesCraniosynostosisdeveloping countriesglobal healthneurosurgerypaediatrics

Identifiers

PMID38249946
PMCPMC10798110

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.