Evidence map›Paper›PMID 38249919›Full record

ArticleJournal of thoracic disease2023

Survival following acute type A aortic dissection: a multicenter study.

Francesco Nappi, Ivancarmine Gambardella, Sanjeet Singh Avtaar Singh, Antonio Salsano, Francesco Santini, Cristiano Spadaccio, Fausto Biancari, Joaquin Dominguez, Antonio Fiore

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07623213 (Artificial Intelligence Multimodal Prediction Model-Guided Intensified Follow-up Strategy for 1-Year Outcomes After Surgery for Acute Type A Aortic Dissection), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07623213 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Artificial Intelligence Multimodal Prediction Model-Guided Intensified Follow-up Strategy for 1-Year Outcomes After Surgery for Acute Type A Aortic Dissection: A Multicenter Randomized Controlled Trial

TypeinterventionalSponsorSecond Affiliated Hospital, Zhejiang University, School of MedicineRan2026 to 2029Enrolled1,314ConditionsAcute Type A Aortic Dissection, Stanford Type A Aortic Dissection, Postoperative Aortic Dissection Follow-upArmsUsual Postoperative Follow-up Strategy, AI Prediction Model-Guided Intensified Follow-up Strategy
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Radiographic phenotyping of healthy and diseased aortas.Journal of cardiovascular imaging · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 5 countries.

Francesco Nappi *Department of Cardiac Surgery, Centre Cardiologique du Nord, Saint-Denis, France.
Ivancarmine Gambardella *Department of Cardiothoracic Surgery, Weill Cornell Medicine-New York, Presbyterian Medical Center, New York, NY, USA.
Sanjeet Singh Avtaar SinghDepartment of Cardiothoracic Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK.
Antonio SalsanoDivision of Cardiac Surgery, Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.
Francesco SantiniDivision of Cardiac Surgery, Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.
Cristiano SpadaccioDepartment of Cardiothoracic Surgery, Mayo Clinic, Rochester, USA.
Fausto BiancariHeart and Lung Center, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Joaquin DominguezDepartment of Vascular Surgery, Centre Cardiologique du Nord, Saint-Denis, France.
Antonio FioreDepartment of Cardiac Surgery, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, Créteil, France.
Centre Cardiologique du Nord · FROspedale Policlinico San Martino · ITEdinburgh Royal Infirmary · GBHelsinki University Hospital · FIHôpitaux Universitaires Henri-Mondor · FRMayo Clinic · USWeill Cornell Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: While surgery is almost always indicated for acute type A aortic dissections (ATAADs), the extent of surgery is often debated, with some surgeons preferring a conservative option and others preferring a more radical option This study aims to assess the outcome after surgery for ATAAD and the prognostic impact of surgical strategy (with Methods: Data was gathered between 1 January 2005 and 31 December 2021 and retrospectively analyzed with multivariable logistic and Cox regression to ascertain risk factors and survival respectively. Results: A total of 601 patients underwent type A aortic dissection repair across the recruiting centers with an operative mortality of 24.3% (146 patients) which was considerably linked with the clinical condition at presentation. In-hospital mortality was 23.1% for ascending and root replacement alone Conclusions: Surgery for ATAAD still confers a relatively high mortality. In our study, there was a higher stroke rate associated with patients who underwent arch replacements at the time of dissection despite them being younger. The choice of repair with or without arch replacement should be individualized to the patient and the severity of clinical status presentation.

Indexed as

Acute type A aortic dissection (ATAAD)aortic root and arch repairascending aorta replacement (AAR)total arch replacement procedure (TARP)valve-sparing aorta replacement

Identifiers

PMID38249919
PMCPMC10797382
OpenAlexW4390349956

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.