Evidence map›Paper›PMID 38249786›Full record

ArticleMedical research archives2023

Evaluation of common clinical and hemodynamic parameters to pulmonary capillary wedge pressures in patients undergoing right heart catheterization.

Kyle M Hocking, Jessica Huston, Jeffery Schmeckpeper, Monica Polcz, Marisa Case, Meghan Breed, Lexie Vaughn, Dawson Wervey, Colleen Brophy, JoAnn Lindenfeld and 1 more

Open access · diamondAbstract read
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Article in Medical research archives, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Kyle M HockingDepartment of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Jessica HustonDepartment of Medicine, Division of Cardiovascular Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Jeffery SchmeckpeperDepartment of Medicine, Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Monica PolczDepartment of Surgery, Atrium Health, Carolinas Medical Center, Charlotte, NC, USA.
Marisa CaseDepartment of Anesthesiology, Division of Critical Care, Vanderbilt University Medical Center, Nashville, TN, USA.
Meghan BreedDepartment of Emergency Medicine, TriStar Skyline Medical Center, Nashville, TN, USA.
Lexie VaughnDepartment of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Dawson WerveyDepartment of Anesthesiology, Division of Critical Care, Vanderbilt University Medical Center, Nashville, TN, USA.
Colleen BrophyDepartment of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
JoAnn LindenfeldDepartment of Medicine, Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Bret D AlvisDepartment of Surgery, Atrium Health, Carolinas Medical Center, Charlotte, NC, USA.
Vanderbilt University Medical Center · USCarolinas Medical Center · USUniversity of Pittsburgh Medical Center · US

Funding

Non-Invasive Venous Waveform Analysis (NIVA) in patients with Heart Failure (HF)R44HL140669 · NHLBI · VOLUMETRIX, LLC · PI HOCKING, KYLE MITCHELL, LINDENFELD, JOANN · 2018 to 2025
$5.1M
Venous Waveform Analysis to Predict Volume OverloadR01HL148244 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Bret D. Alvis · 2019 to 2026
$3.4M
NHLBI NIH HHS R01 HL148244NHLBI NIH HHS R44 HL140669
6 · The paper itself

Abstract

Introduction: A cornerstone of heart failure assessment is the right heart catheterization and the pulmonary capillary wedge pressure measurement it can provide. Clinical and hemodynamic parameters such as weight and jugular venous distention are less invasive measures often used to diagnose, manage, and treat these patients. To date, there is little data looking at the association of these key parameters to measured pulmonary capillary wedge pressure (PCWP). This is a large, retrospective, secondary analysis of a right heart catheterization database comparing clinical and hemodynamic parameters against measured PCWP in heart failure patients. Methods: A total of 538 subjects were included in this secondary analysis. Spearman's Rho analysis of each clinical and hemodynamic variable was used to compare their association to the documented PCWP. Variables analyzed included weight, body mass index (BMI), jugular venous distention (JVD), creatinine, edema grade, right atrial pressure (RAP), pulmonary artery systolic pressure (PASP), systemic vascular resistance, pulmonary vascular resistance, cardiac output (thermal and Fick), systolic blood pressure, diastolic blood pressure, heart rate, respiratory rate, oxygen saturation (SpO Results: Ten out of 17 selected parameters had a statistically significant association with measured PCWP values. PADP had the strongest association (0.73, p<0.0001), followed by RAP and PASP (0.69, p<0.0001 and 0.67, p<0.0001, respectively). Other significant parameters included weight (0.2, p<0.001), BMI (0.2, p<0.001), SpO Conclusion: This retrospective analysis clarifies the associations of commonly used clinical and hemodynamic parameters to the clinically used gold standard for volume assessment in heart failure patients, PCWP.

Indexed as

Congestionheart failurePCWPright heart catheterization

Identifiers

PMID38249786
PMCPMC10795841
OpenAlexW4312614315

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.