Evidence map›Paper›PMID 38249777›Full record

ArticleOxford open materials science2024

Metal-based porous hydrogels for highly conductive biomaterial scaffolds.

Christina M Tringides, Marjolaine Boulingre, David J Mooney

Abstract read
In one paragraph

Article in Oxford open materials science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Hydrogel-based neural engineering for skin wound healing.Frontiers in cell and developmental biology · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christina M TringidesProgram in Biophysics, Harvard University, Cambridge, MA 02138, USA.
Marjolaine BoulingreJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.
David J MooneyWyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, MA 02115, USA.

Funding

MOLECULAR BIOPHYSICS TRAINING GRANTT32GM008313 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI MURTHY, VENKATESH N · 1989 to 2023
$14.6M
ENGINEERING SKELETAL MUSCLE WITH BIODEGRADABLE HYDROGELSR01DE013349 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOONEY, DAVID J · 2000 to 2022
$9.3M
POLYMERIC MATRICES WITH DEFINED CELL ADHESION AND MECHANR01DE013033 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOONEY, DAVID J · 1998 to 2018
$3.0M
NIDCR NIH HHS R01 DE013033NIDCR NIH HHS R01 DE013349NIGMS NIH HHS T32 GM008313
6 · The paper itself

Abstract

Multielectrode arrays are fabricated from thin films of highly conductive and ductile metals which cannot mimic the natural environment of biological tissues. These properties limit the conformability of the electrode to the underlying target tissue, and present challenges in developing seamless interfaces. By introducing porous, hydrogel materials that are embedded with metal additives, highly conductive hydrogels can be formed. Tuning the hydrogel composition, % volume and aspect ratio of different additive(s), and the processing conditions of these composite materials can alter the mechanical and electrical properties. The resulting materials have a high surface area, and can be used as biomaterial scaffolds to support the growth of macrophages for 5 days. Further optimization can enable the use of the materials for the electrodes in implantable arrays, or as living electrode platforms to study and modulate various cellular cultures. These advancements would benefit both

Indexed as

3D biologybiohybrid electronicsbiomaterialscompositesconductive scaffoldshydrogelstissue engineering

Identifiers

PMID38249777
PMCPMC10798674

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.