Evidence map›Paper›PMID 38249638›Full record

ArticlePediatric gastroenterology, hepatology & nutrition2024

Identification of Autoantigens in Pediatric Gastric Juices.

Hee-Shang Youn, Jin-Su Jun, Jung Sook Yeom, Ji Sook Park, Jae-Young Lim, Hyang-Ok Woo, Jung-Wook Yang, Seung-Chul Baik, Woo-Kon Lee, Ji-Hyun Seo

Open access · diamondAbstract read
In one paragraph

Article in Pediatric gastroenterology, hepatology & nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hee-Shang YounDepartment of Pediatrics, Gyeongsang National University School of Medicine, Gyeongsang National University Hospital, Gyeongsang Institute of Health Science, Jinju, Korea.ORCID https://orcid.org/0000-0002-5498-838X
Jin-Su JunDepartment of Pediatrics, Gyeongsang National University School of Medicine, Gyeongsang National University Hospital, Gyeongsang Institute of Health Science, Jinju, Korea.ORCID https://orcid.org/0000-0002-6382-6286
Jung Sook YeomDepartment of Pediatrics, Gyeongsang National University School of Medicine, Gyeongsang National University Hospital, Gyeongsang Institute of Health Science, Jinju, Korea.ORCID https://orcid.org/0000-0003-0688-7493
Ji Sook ParkDepartment of Pediatrics, Gyeongsang National University School of Medicine, Gyeongsang National University Hospital, Gyeongsang Institute of Health Science, Jinju, Korea.ORCID https://orcid.org/0000-0002-4704-2246
Jae-Young LimDepartment of Pediatrics, Gyeongsang National University School of Medicine, Gyeongsang National University Hospital, Gyeongsang Institute of Health Science, Jinju, Korea.ORCID https://orcid.org/0000-0001-5728-4604
Hyang-Ok WooDepartment of Pediatrics, Gyeongsang National University School of Medicine, Gyeongsang National University Hospital, Gyeongsang Institute of Health Science, Jinju, Korea.ORCID https://orcid.org/0000-0001-8849-9341
Jung-Wook YangDepartment of Pathology, Gyeongsang National University School of Medicine, Gyeongsang Institute of Health Science, Jinju, Korea.ORCID https://orcid.org/0000-0002-9698-3667
Seung-Chul BaikDepartment of Microbiology, Gyeongsang National University School of Medicine, Gyeongsang Institute of Health Science, Jinju, Korea.ORCID https://orcid.org/0000-0001-6033-4078
Woo-Kon LeeDepartment of Microbiology, Gyeongsang National University School of Medicine, Gyeongsang Institute of Health Science, Jinju, Korea.ORCID https://orcid.org/0000-0003-3913-2265
Ji-Hyun SeoDepartment of Pediatrics, Gyeongsang National University School of Medicine, Gyeongsang National University Hospital, Gyeongsang Institute of Health Science, Jinju, Korea.ORCID https://orcid.org/0000-0002-0691-3957
Gyeongsang National University Hospital · KRGyeongsang National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to investigate the presence of autoantigens in the gastric juices of children. Methods: Gastric juice and serum samples were obtained from 53 children <15 years of age who underwent gastric endoscopy. Among these, 8, 22, and 23 participants were in the age groups 0-5, 6-10, and 11-15 years, respectively. These samples were analyzed using two-dimensional electrophoresis (2-DE), immunoblot analysis, and matrix-assisted laser desorption ionization-time of-flight mass spectrometry. Furthermore, we reviewed the histopathological findings and urease test results and compared them with the results of 2-DE and immunoblot analysis. Results: There were no statistically significant differences in urease test positivity, grades of chronic gastritis, active gastritis, or Conclusion: Three enzymes, which are normally secreted under acidic conditions were identified as autoantigens. Further investigation of the pathophysiology and function of autoantigens in the stomach is required.

Indexed as

AutoantigensChildrenGastric juiceGastritisHelicobacter pylori

Identifiers

PMID38249638
PMCPMC10796257
OpenAlexW4390894080

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.