Evidence map›Paper›PMID 38249123›Full record

ArticleAnimal cells and systems2024

Eugenol ameliorates uveitis in mice with experimental autoimmune encephalomyelitis through the suppression of key inflammatory genes.

Sungmoo Hong, Kyungsook Jung, Meejung Ahn, Jeongtae Kim, Changjong Moon, Taekyun Shin

Open access · goldAbstract read
In one paragraph

Article in Animal cells and systems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Sungmoo HongCollege of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju, Republic of Korea.ORCID https://orcid.org/0009-0007-3906-3526
Kyungsook JungFunctional Biomaterials Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup-si, Republic of Korea.ORCID https://orcid.org/0000-0002-0723-805X
Meejung AhnDepartment of Animal Science, College of Life Science, Sangji University, Wonju, Republic of Korea.ORCID https://orcid.org/0000-0002-7302-9694
Jeongtae KimDepartment of Anatomy, Kosin University College of Medicine, Busan, Republic of Korea.ORCID https://orcid.org/0000-0003-2238-1038
Changjong MoonDepartment of Veterinary Anatomy and Animal Behavior, College of Veterinary Medicine and BK21 Plus Project Team, Chonnam National University, Gwangju, Republic of Korea.ORCID https://orcid.org/0000-0003-2451-0374
Taekyun ShinCollege of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju, Republic of Korea.ORCID https://orcid.org/0000-0002-9851-4354
Jeju National University · KRChonnam National University · KRKorea Research Institute of Bioscience and Biotechnology · KRKosin University · KRSangji University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Visual impairment associated with uveitis is among the potential complications in multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). Bioinformatics analyses have shown that some hub genes are closely associated with the molecular mechanisms underlying uveitis in EAE. This study evaluated whether 4-allyl-2-methoxyphenol (eugenol) can mitigate the pathogenesis of uveitis in EAE through the interruption of key uveitogenic gene expression. Myelin oligodendrocyte glycoprotein

Indexed as

Anti-inflammationeugenolexperimental autoimmune encephalomyelitisneuroinflammationuveitis

Identifiers

PMID38249123
PMCPMC10798281
OpenAlexW4390984656

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.