Evidence map›Paper›PMID 38248759›Full record

ArticleJournal of personalized medicine2023

Personalized Predictive Hemodynamic Management for Gynecologic Oncologic Surgery: Feasibility of Cost-Benefit Derivatives of Digital Medical Devices.

Luciano Frassanito, Rossella Di Bidino, Francesco Vassalli, Kristian Michnacs, Pietro Paolo Giuri, Bruno Antonio Zanfini, Stefano Catarci, Nicoletta Filetici, Chiara Sonnino, Americo Cicchetti and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Luciano FrassanitoDepartment of Emergency, Anesthesiologic and Intensive Care Sciences, IRCCS Fondazione Policlinico A. Gemelli, Largo A. Gemelli 8, 00168 Rome, Italy.ORCID 0000-0001-6406-2591
Rossella Di BidinoDepartment of Health Technology, IRCCS Fondazione Policlinico A. Gemelli, 00168 Rome, Italy.ORCID 0000-0001-9773-856X
Francesco VassalliDepartment of Critical Care and Perinatal Medicine, IRCCS Istituto G. Gaslini, 16147 Genoa, Italy.ORCID 0000-0001-5067-9427
Kristian MichnacsEdwards Lifescience GmbH, 85748 München, Germany.
Pietro Paolo GiuriDepartment of Emergency, Anesthesiologic and Intensive Care Sciences, IRCCS Fondazione Policlinico A. Gemelli, Largo A. Gemelli 8, 00168 Rome, Italy.ORCID 0000-0003-3644-1425
Bruno Antonio ZanfiniDepartment of Emergency, Anesthesiologic and Intensive Care Sciences, IRCCS Fondazione Policlinico A. Gemelli, Largo A. Gemelli 8, 00168 Rome, Italy.ORCID 0000-0003-1312-5382
Stefano CatarciDepartment of Emergency, Anesthesiologic and Intensive Care Sciences, IRCCS Fondazione Policlinico A. Gemelli, Largo A. Gemelli 8, 00168 Rome, Italy.ORCID 0000-0002-3466-6527
Nicoletta FileticiDepartment of Emergency, Anesthesiologic and Intensive Care Sciences, IRCCS Fondazione Policlinico A. Gemelli, Largo A. Gemelli 8, 00168 Rome, Italy.
Chiara SonninoDepartment of Emergency, Anesthesiologic and Intensive Care Sciences, IRCCS Fondazione Policlinico A. Gemelli, Largo A. Gemelli 8, 00168 Rome, Italy.ORCID 0000-0002-6084-5529
Americo CicchettiDepartment of Management Studies, Faculty of Economics, Catholic University of Sacred Heart, 00168 Rome, Italy.
Giovanni ArcuriDepartment of Health Technology, IRCCS Fondazione Policlinico A. Gemelli, 00168 Rome, Italy.
Gaetano DraisciDepartment of Emergency, Anesthesiologic and Intensive Care Sciences, IRCCS Fondazione Policlinico A. Gemelli, Largo A. Gemelli 8, 00168 Rome, Italy.
Agostino Gemelli University Polyclinic · ITIstituto Giannina Gaslini · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntraoperative hypotension is associated with increased perioperative complications, hospital length of stay (LOS) and healthcare expenditure in gynecologic surgery. We tested the hypothesis that the adoption of a machine learning-based warning algorithm (hypotension prediction index-HPI) might yield an economic advantage, with a reduction in adverse outcomes that outweighs the costs for its implementation as a medical device.

methodsA retrospective-matched cohort cost-benefit Italian study in gynecologic surgery was conducted. Sixty-six female patients treated with standard goal-directed therapy (GDT) were matched in a 2:1 ratio with thirty-three patients treated with HPI based on ASA status, diagnosis, procedure, surgical duration and age.

resultsThe most relevant contributor to medical costs was operating room occupation (46%), followed by hospital stay (30%) and medical devices (15%). Patients in the HPI group had EURO 300 greater outlay for medical devices without major differences in total costs (GDT 5425 (3505, 8127), HPI 5227 (4201, 7023)

conclusionsImplementation of HPI is associated with a scenario of cost neutrality, with possible economic advantage in high-risk settings.

Indexed as

gynecologic oncologic surgeryhealthcare resource utilizationintraoperative hypotensionlength of staymachine learning

Identifiers

PMID38248759
PMCPMC10820080
OpenAlexW4390466900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.