Evidence map›Paper›PMID 38248648›Full record

ArticleMarine drugs2023

OSMAC Method to Assess Impact of Culture Parameters on Metabolomic Diversity and Biological Activity of Marine-Derived Actinobacteria.

Alexandre Le Loarer, Laurent Dufossé, Jérôme Bignon, Michel Frédérich, Allison Ledoux, Mireille Fouillaud, Anne Gauvin-Bialecki

Abstract read
In one paragraph

Article in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. New Marine Actinobacteria Strain,Microorganisms · 2025
    Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexandre Le LoarerLaboratory of Chemistry and Biotechnology of Natural Products, Faculty of Sciences and Technology, University of La Réunion, 15 Avenue René Cassin, CS 92003, CEDEX 09, 97744 Saint-Denis, France.
Laurent DufosséLaboratory of Chemistry and Biotechnology of Natural Products, Faculty of Sciences and Technology, University of La Réunion, 15 Avenue René Cassin, CS 92003, CEDEX 09, 97744 Saint-Denis, France.ORCID 0000-0001-7392-355X
Jérôme BignonInstitute of Chemistry of Natural Substances (ICSN), CNRS UPR 2301, Université Paris-Saclay, 1, av. de la Terrasse, 91198 Gif-sur-Yvette, France.ORCID 0000-0002-6294-9671
Michel FrédérichPharmacognosy Laboratory, Department of Pharmacy, Centre Interfacultaire de Recherche sur le Médicament (CIRM), University of Liège, Campus du Sart-Tilman, Quartier Hôpital, Avenue Hippocrate, 15, B36, 4000 Liege, Belgium.ORCID 0000-0002-0770-9990
Allison LedouxPharmacognosy Laboratory, Department of Pharmacy, Centre Interfacultaire de Recherche sur le Médicament (CIRM), University of Liège, Campus du Sart-Tilman, Quartier Hôpital, Avenue Hippocrate, 15, B36, 4000 Liege, Belgium.ORCID 0000-0002-4052-6336
Mireille FouillaudLaboratory of Chemistry and Biotechnology of Natural Products, Faculty of Sciences and Technology, University of La Réunion, 15 Avenue René Cassin, CS 92003, CEDEX 09, 97744 Saint-Denis, France.ORCID 0000-0002-0562-2154
Anne Gauvin-BialeckiLaboratory of Chemistry and Biotechnology of Natural Products, Faculty of Sciences and Technology, University of La Réunion, 15 Avenue René Cassin, CS 92003, CEDEX 09, 97744 Saint-Denis, France.ORCID 0000-0001-5188-0704

Funding

European Regional Development Funds GURDTI 2018-1828-0002370
6 · The paper itself

Abstract

Actinobacteria are known for their production of bioactive specialized metabolites, but they are still under-exploited. This study uses the "One Strain Many Compounds" (OSMAC) method to explore the potential of three preselected marine-derived actinobacteria:

Indexed as

ActinobacteriaAntimalarialsMicromonosporaMicromonosporaceaeBacteriaMetabolomicsAntimalarialsantiplasmodial activitycytotoxic activitymarine-derived actinobacteriaMicromonosporamolecular networkOSMAC methodSalinisporaspecialized metabolites

Identifiers

PMID38248648
PMCPMC10817652

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.