Evidence map›Paper›PMID 38248423›Full record

ArticleBiosensors2024

Gram-Positive Bacterial Membrane-Based Biosensor for Multimodal Investigation of Membrane-Antibiotic Interactions.

Samavi Farnush Bint-E-Naser, Zeinab Jushkun Mohamed, Zhongmou Chao, Karan Bali, Róisín M Owens, Susan Daniel

Abstract read
In one paragraph

Article in Biosensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Samavi Farnush Bint-E-NaserRobert F. Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0001-6838-0124
Zeinab Jushkun MohamedMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.
Zhongmou ChaoRobert F. Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA.
Karan BaliDepartment of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB3 0AS, UK.
Róisín M OwensDepartment of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB3 0AS, UK.ORCID 0000-0001-7856-2108
Susan DanielRobert F. Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0001-7773-0835

Funding

Establishing a Gram-Negative Permeation Rule Set Leveraging a Unique Small Molecule LibraryR01AI136805 · NIAID · VENATORX PHARMACEUTICALS, INC. · PI BOYD, STEVEN ARMEN · 2018 to 2022
$7.4M
NIAID NIH HHS R01 AI136805NIH HHS R01AI136805
6 · The paper itself

Abstract

As membrane-mediated antibiotic resistance continues to evolve in Gram-positive bacteria, the development of new approaches to elucidate the membrane properties involved in antibiotic resistance has become critical. Membrane vesicles (MVs) secreted by the cytoplasmic membrane of Gram-positive bacteria contain native components, preserving lipid and protein diversity, nucleic acids, and sometimes virulence factors. Thus, MV-derived membrane platforms present a great model for Gram-positive bacterial membranes. In this work, we report the development of a planar bacterial cytoplasmic membrane-based biosensor using MVs isolated from the

Indexed as

Anti-Bacterial AgentsDaptomycinCell MembraneGram-Positive BacteriaIonsAnti-Bacterial AgentsDaptomycinIonsantibiotic sensingdaptomycinGram-positive bacteriamembrane vesiclesmicroelectrode arrayorganic electronicpermeabilitysupported lipid bilayer

Identifiers

PMID38248423
PMCPMC10813107

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.