Evidence map›Paper›PMID 38248225›Full record

ArticleBrain sciences2023

Mortality Prediction of Patients with Subarachnoid Hemorrhage Using a Deep Learning Model Based on an Initial Brain CT Scan.

Sergio García-García, Santiago Cepeda, Dominik Müller, Alejandra Mosteiro, Ramón Torné, Silvia Agudo, Natalia de la Torre, Ignacio Arrese, Rosario Sarabia

Abstract read
In one paragraph

Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sergio García-GarcíaNeurosurgery Department, Rio Hortega University Hospital, 47012 Valladolid, Spain.ORCID 0000-0003-2356-5306
Santiago CepedaNeurosurgery Department, Rio Hortega University Hospital, 47012 Valladolid, Spain.ORCID 0000-0003-1667-8548
Dominik MüllerIT-Infrastructure for Translational Medical Research, University of Augsburg, 86159 Augsburg, Germany.ORCID 0000-0003-0838-9885
Alejandra MosteiroNeurosurgery Department, Hospital Clinic de Barcelona, 08036 Barcelona, Spain.
Ramón TornéNeurosurgery Department, Hospital Clinic de Barcelona, 08036 Barcelona, Spain.ORCID 0000-0001-7932-2528
Silvia AgudoNeurosurgery Department, Rio Hortega University Hospital, 47012 Valladolid, Spain.
Natalia de la TorreNeurosurgery Department, Rio Hortega University Hospital, 47012 Valladolid, Spain.
Ignacio ArreseNeurosurgery Department, Rio Hortega University Hospital, 47012 Valladolid, Spain.
Rosario SarabiaNeurosurgery Department, Rio Hortega University Hospital, 47012 Valladolid, Spain.ORCID 0000-0003-2576-7518

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSubarachnoid hemorrhage (SAH) entails high morbidity and mortality rates. Convolutional neural networks (CNN) are capable of generating highly accurate predictions from imaging data. Our objective was to predict mortality in SAH patients by processing initial CT scans using a CNN-based algorithm.

methodsWe conducted a retrospective multicentric study of a consecutive cohort of patients with SAH. Demographic, clinical and radiological variables were analyzed. Preprocessed baseline CT scan images were used as the input for training using the AUCMEDI framework. Our model's architecture leveraged a DenseNet121 structure, employing transfer learning principles. The output variable was mortality in the first three months.

resultsImages from 219 patients were processed; 175 for training and validation and 44 for the model's evaluation. Of the patients, 52% (115/219) were female and the median age was 58 (SD = 13.06) years. In total, 18.5% (39/219) had idiopathic SAH. The mortality rate was 28.5% (63/219). The model showed good accuracy at predicting mortality in SAH patients when exclusively using the images of the initial CT scan (accuracy = 74%, F1 = 75% and AUC = 82%).

conclusionModern image processing techniques based on AI and CNN make it possible to predict mortality in SAH patients with high accuracy using CT scan images as the only input. These models might be optimized by including more data and patients, resulting in better training, development and performance on tasks that are beyond the skills of conventional clinical knowledge.

Indexed as

artificial intelligenceconvolutional neural networksCT scanmortalityprognosissubarachnoid hemorrhage

Identifiers

PMID38248225
PMCPMC10812955

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.