ArticleDiagnostics (Basel, Switzerland)2024
Ultrasound in the Diagnosis of Non-Expandable Lung: A Prospective Observational Study of M-Mode, B-Mode, and 2D-Shear Wave Elastography.
Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 17 citations in OpenAlex.
- Ultrasound Techniques for Suspected Malignant Pleural Effusion and Nonexpandable Lung.CHEST pulmonary · 2026Review
- Thoracic ultrasound elastography in pleural and subpleural diseases: a narrative review.Journal of ultrasound · 2026Review
- Advances in thoracic ultrasound.The European respiratory journal · 2026Article
- Review
- Lung Ultrasound for Pleural Effusion in Cancer Patients: Advanced Ultrasound for Pleural Lesions-A Narrative Review.Cancers · 2025Review
- Ultrasound innovations in diaphragm assessment: an integrative review of expanding clinical applications.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- Article
- The road less travelled: thoracic ultrasound, advanced imaging and artificial intelligence for early diagnosis of non-expandable lung in malignant pleural effusion.Breathe (Sheffield, England) · 2025Article
- Current Trends in Treating Malignant Pleural Effusion: Evidence, Guidelines, and Best Practice Recommendations.JCO oncology practice · 2025Review
- Advanced imaging techniques and artificial intelligence in pleural diseases: a narrative review.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- Thoracic Ultrasound for Pre-Procedural Dynamic Assessment of Non-Expandable Lung: A Non-Invasive, Real-Time and Multifaceted Diagnostic Tool.Journal of clinical medicine · 2025Review
- A patient-centred approach to malignant pleural effusion.European clinical respiratory journal · 2025Review
- Patient-Reported Outcome Measures in Patients with and without Non-Expandable Lung Secondary to Malignant Pleural Effusion-A Single-Centre Observational Study.Diagnostics (Basel, Switzerland) · 2024Article
- Malignant Pleural Effusion: A Multidisciplinary Approach.Open respiratory archivesReview
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNon-expandable lung (NEL) has severe implications for patient symptoms and impaired lung function, as well as crucial implications for the management of malignant pleural effusion (MPE). Indwelling pleural catheters have shown good symptom relief for patients with NEL; hence, identifying patients early in their disease is vital. With the inability of the lung to achieve pleural apposition following thoracentesis and the formation of a hydropneumothorax, traditionally, chest X-ray and clinical symptoms have been used to make the diagnosis following thoracentesis. It is our aim to investigate whether ultrasound measurement of lung movement during respiration can predict NEL before thoracentesis, thereby aiding clinicians in their planning for the optimal treatment of affected patients.
methodsA total of 49 patients were consecutively included in a single-centre trial performed at a pleural clinic. Patients underwent protocolled ultrasound assessment pre-thoracentesis with measurements of lung and diaphragm movement and shear wave elastography measurements of the pleura and pleural effusion at the planned site of thoracentesis.
resultsM-mode measurements of lung movement provided the best diagnostic ROC-curve results, with an AUC of 0.81. Internal validity showed good results utilising the calibration belt test and Brier test.
conclusionM-mode measurement of lung movement shows promise in diagnosing NEL before thoracentesis in patients with known or suspected MPE. A validation cohort is needed to confirm the results.
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Registered trials
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