Evidence map›Paper›PMID 38248066›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Palm-Sized Wireless Transient Elastography System with Real-Time B-Mode Ultrasound Imaging Guidance: Toward Point-of-Care Liver Fibrosis Assessment.

Zi-Hao Huang, Li-Ke Wang, Shang-Yu Cai, Hao-Xin Chen, Yongjin Zhou, Lok-Kan Cheng, Yi-Wei Lin, Ming-Hua Zheng, Yong-Ping Zheng

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Identification of Hepatic Fibrosis and Steatosis via A Point-of-Care Transient Elastography System With Integrated AI.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Observational
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Zi-Hao HuangDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China.
Li-Ke WangDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China.
Shang-Yu CaiSchool of Biomedical Engineering, Medical School, Shenzhen University, Shenzhen 518000, China.
Hao-Xin ChenSchool of Biomedical Engineering, Medical School, Shenzhen University, Shenzhen 518000, China.
Yongjin ZhouSchool of Biomedical Engineering, Medical School, Shenzhen University, Shenzhen 518000, China.
Lok-Kan ChengDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China.
Yi-Wei LinMAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Ming-Hua ZhengMAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.ORCID 0000-0003-4984-2631
Yong-Ping ZhengDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China.ORCID 0000-0002-3407-9226
Hong Kong Polytechnic University · HKShenzhen University · CNWenzhou Medical University · CN

Funding

Tai Hung Fai Charitable Foundation for Henry G. 654 Leong Professor in Biomedical Engineering 847L
6 · The paper itself

Abstract

Transient elastography (TE), recommended by the WHO, is an established method for characterizing liver fibrosis via liver stiffness measurement (LSM). However, technical barriers remain towards point-of-care application, as conventional TE requires wired connections, possesses a bulky size, and lacks adequate imaging guidance for precise liver localization. In this work, we report the design, phantom validation, and clinical evaluation of a palm-sized TE system that enables simultaneous B-mode imaging and LSM. The performance of this system was validated experimentally using tissue-equivalent reference phantoms (1.45-75 kPa). Comparative studies against other liver elastography techniques, including conventional TE and two-dimensional shear wave elastography (2D-SWE), were performed to evaluate its reliability and validity in adults with various chronic liver diseases. Intra- and inter-operator reliability of LSM were established by an elastography expert and a novice. A good agreement was observed between the Young's modulus reported by the phantom manufacturer and this system (bias: 1.1-8.6%). Among 121 patients, liver stiffness measured by this system and conventional TE were highly correlated (

Indexed as

liver elastographyliver fibrosisliver stiffness measurementpoint-of-care ultrasoundtransient elastographywireless ultrasound

Identifiers

PMID38248066
PMCPMC11154523
OpenAlexW4390875966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.