Evidence map›Paper›PMID 38248059›Full record

ReviewDiagnostics (Basel, Switzerland)2024

Radiomics and Artificial Intelligence in Radiotheranostics: A Review of Applications for Radioligands Targeting Somatostatin Receptors and Prostate-Specific Membrane Antigens.

Elmira Yazdani, Parham Geramifar, Najme Karamzade-Ziarati, Mahdi Sadeghi, Payam Amini, Arman Rahmim

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
19.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Review
  3. Evolving SPECT-CT technology.The British journal of radiology · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. The Role of Artificial Intelligence in Theranostics.Journal of nuclear medicine technology · 2025
    Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Automated segmentation of lesions and organs at risk on [Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Elmira YazdaniMedical Physics Department, School of Medicine, Iran University of Medical Sciences, Tehran 14496-14535, Iran.
Parham GeramifarResearch Center for Nuclear Medicine, Tehran University of Medical Sciences, Tehran 14117-13135, Iran.ORCID 0000-0002-7607-6859
Najme Karamzade-ZiaratiResearch Center for Nuclear Medicine, Tehran University of Medical Sciences, Tehran 14117-13135, Iran.ORCID 0000-0002-0432-6193
Mahdi SadeghiMedical Physics Department, School of Medicine, Iran University of Medical Sciences, Tehran 14496-14535, Iran.ORCID 0000-0001-5055-4544
Payam AminiDepartment of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran 14496-14535, Iran.
Arman RahmimDepartment of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC V5Z 1L3, Canada.
Iran University of Medical Sciences · IRTehran University of Medical Sciences · IRUniversity of British Columbia · CA

Funding

Iran National Science Foundation 4020727
6 · The paper itself

Abstract

Radiotheranostics refers to the pairing of radioactive imaging biomarkers with radioactive therapeutic compounds that deliver ionizing radiation. Given the introduction of very promising radiopharmaceuticals, the radiotheranostics approach is creating a novel paradigm in personalized, targeted radionuclide therapies (TRTs), also known as radiopharmaceuticals (RPTs). Radiotherapeutic pairs targeting somatostatin receptors (SSTR) and prostate-specific membrane antigens (PSMA) are increasingly being used to diagnose and treat patients with metastatic neuroendocrine tumors (NETs) and prostate cancer. In parallel, radiomics and artificial intelligence (AI), as important areas in quantitative image analysis, are paving the way for significantly enhanced workflows in diagnostic and theranostic fields, from data and image processing to clinical decision support, improving patient selection, personalized treatment strategies, response prediction, and prognostication. Furthermore, AI has the potential for tremendous effectiveness in patient dosimetry which copes with complex and time-consuming tasks in the RPT workflow. The present work provides a comprehensive overview of radiomics and AI application in radiotheranostics, focusing on pairs of SSTR- or PSMA-targeting radioligands, describing the fundamental concepts and specific imaging/treatment features. Our review includes ligands radiolabeled by

Indexed as

artificial intelligencepersonalized dosimetryPSMAradiomicsradiotheranosticsSSTR

Identifiers

PMID38248059
PMCPMC10814892
OpenAlexW4390885406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.