ArticleBioengineering (Basel, Switzerland)2023
Mechanical Behaviour of Plantar Adipose Tissue: From Experimental Tests to Constitutive Analysis.
Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Towards a consensus atlas of human and mouse adipose tissue at single-cell resolution.Nature metabolism · 2025Guideline
- Biomechanics of Human Plantar Skin: Experimental and Constitutive Analysis.Annals of biomedical engineering · 2026Article
- The influence of infrapatellar fat pad resection on knee joint friction and damping: An in vitro study in New Zealand white rabbits.Journal of the mechanical behavior of biomedical materials · 2026Article
- Preliminary Reference Values for Plantar Fat Pad Thickness Beneath the Metatarsal Heads and Its Relationship with Body Mass Index.Healthcare (Basel, Switzerland) · 2025Article
- Correction: Pettenuzzo et al. Mechanical Behaviour of Plantar Adipose Tissue: From Experimental Tests to Constitutive Analysis.Bioengineering (Basel, Switzerland) · 2025Article
- Mechanical characterization of porcine ureter for the evaluation of tissue-engineering applications.Frontiers in bioengineering and biotechnology · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
Plantar adipose tissue is a connective tissue whose structural configuration changes according to the foot region (rare or forefoot) and is related to its mechanical role, providing a damping system able to adsorb foot impact and bear the body weight. Considering this, the present work aims at fully describing the plantar adipose tissue's behaviour and developing a proper constitutive formulation. Unconfined compression tests and indentation tests have been performed on samples harvested from human donors and cadavers. Experimental results provided the initial/final elastic modulus for each specimen and assessed the non-linear and time-dependent behaviour of the tissue. The different foot regions were investigated, and the main differences were observed when comparing the elastic moduli, especially the final elastic ones. It resulted in a higher level for the medial region (89 ± 77 MPa) compared to the others (from 51 ± 29 MPa for the heel pad to 11 ± 7 for the metatarsal). Finally, results have been used to define a visco-hyperelastic constitutive model, whose hyperelastic component, which describes tissue non-linear behaviour, was described using an Ogden formulation. The identified and validated tissue constitutive parameters could serve, in the early future, for the computational model of the healthy foot.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.