Evidence map›Paper›PMID 38247895›Full record

ArticleBioengineering (Basel, Switzerland)2023

Epicardial Pulsed Field Ablation of Ganglionated Plexi: Computational and Pre-Clinical Evaluation of a Bipolar Sub-Xiphoid Catheter for the Treatment of Atrial Fibrillation.

Barry O'Brien, John Reilly, Ken Coffey, Ana González-Suárez, Piotr Buchta, Piotr P Buszman, Karolina Lukasik, Jason Tri, Martin van Zyl, Samuel Asirvatham

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Barry O'BrienAtriAN Medical Ltd., Unit 204, Business Innovation Centre, Upper Newcastle, H91 W60E Galway, Ireland.
John ReillyAtriAN Medical Ltd., Unit 204, Business Innovation Centre, Upper Newcastle, H91 W60E Galway, Ireland.
Ken CoffeyAtriAN Medical Ltd., Unit 204, Business Innovation Centre, Upper Newcastle, H91 W60E Galway, Ireland.
Ana González-SuárezTranslational Medical Device Laboratory, School of Medicine, University of Galway, H91 YR71 Galway, Ireland.ORCID 0000-0002-1813-4176
Piotr Buchta3rd Department of Cardiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland.
Piotr P BuszmanCenter for Cardiovascular Research and Development, American Heart of Poland, Kostkowice, Poland.
Karolina LukasikCenter for Cardiovascular Research and Development, American Heart of Poland, Kostkowice, Poland.
Jason TriMayo Clinic, Rochester, MN 55905, USA.
Martin van ZylRoyal Jubilee Hospital, University of British Columbia, Victoria, BC, Canada.
Samuel AsirvathamMayo Clinic, Rochester, MN 55905, USA.
American Heart of Poland · PLMayo Clinic in Arizona · USMedical University of Silesia · PLUniversity of British Columbia · CAValencian International University · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epicardial pulsed field ablation (PFA) of ganglionated plexi (GPs) is being explored as a potential treatment for atrial fibrillation. Initial work using open-chest access with a monopolar ablation device has been completed. This study describes the early development work for a device that can be used with subxiphoid access and deliver bipolar ablation pulses. Electric field computational models have been used for the initial guidance on pulse parameters. An in vivo assessment of these ablation parameters has been performed in an open-chest canine study, while subxiphoid access and navigation of the device has been demonstrated in a porcine model. Results from this acute study have demonstrated the promising potential of this approach.

Indexed as

atrial fibrillationepicardialganglionated plexipulsed field ablationsubxiphoid

Identifiers

PMID38247895
PMCPMC10813135
OpenAlexW4390176285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.