Evidence map›Paper›PMID 38247887›Full record

ArticleBioengineering (Basel, Switzerland)2023

Magnetic Field Intervention Enhances Cellular Migration Rates in Biological Scaffolds.

Amy M Vecheck, Cameron M McNamee, Renee Reijo Pera, Robert J Usselman

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Amy M VecheckDepartment of Biomedical Engineering and Sciences, Florida Institute of Technology, Melbourne, FL 32901, USA.
Cameron M McNameeDepartment of Mathematics, California Institute of Technology, Pasadena, CA 91125, USA.
Renee Reijo PeraMcLaughlin Research Institute, Great Falls, MT 59405, USA.
Robert J UsselmanDepartment of Chemistry and Chemical Engineering, Florida Institute of Technology, Melbourne, FL 32901, USA.ORCID 0009-0007-4824-3975
Florida Institute of Technology · USCalifornia Institute of Technology · USMcLaughlin Research Institute · US

Funding

Air Force Office of Scientific Research FA9550-17-1-0458American Heart Association 15SDG25710461
6 · The paper itself

Abstract

The impact of magnetic fields on cellular function is diverse but can be described at least in part by the radical pair mechanism (RPM), where magnetic field intervention alters reactive oxygen species (ROS) populations and downstream cellular signaling. Here, cellular migration within three-dimensional scaffolds was monitored in an applied oscillating 1.4 MHz radiofrequency (RF) magnetic field with an amplitude of 10 µT and a static 50 µT magnetic field. Given that cellular bioenergetics can be altered based on applied RF magnetic fields, this study focused on a magnetic field configuration that increased cellular respiration. Results suggest that RF accelerated cell clustering and elongation after 1 day, with increased levels of clustering and cellular linkage after 7 days. Cell distribution analysis within the scaffolds revealed that the clustering rate during the first day was increased nearly five times in the RF environment. Electron microscopy provided additional topological information and verified the development of fibrous networks, with a cell-derived matrix (CDM) visualized after 7 days in samples maintained in RF. This work demonstrates time-dependent cellular migration that may be influenced by quantum biology (QB) processes and downstream oxidative signaling, enhancing cellular migration behavior.

Indexed as

3D bioscaffoldscellular migrationcomputer visionimage analysismagnetic mitohormesisquantum biologyradical pair mechanism

Identifiers

PMID38247887
PMCPMC10813414
OpenAlexW4390113956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.