Evidence map›Paper›PMID 38247733›Full record

ReviewBiotech (Basel (Switzerland))2024

Exploring DNA Damage and Repair Mechanisms: A Review with Computational Insights.

Jiawei Chen, Ravi Potlapalli, Heng Quan, Lingtao Chen, Ying Xie, Seyedamin Pouriyeh, Nazmus Sakib, Lichao Liu, Yixin Xie

Open access · goldAbstract readReview
In one paragraph

Review in Biotech (Basel (Switzerland)), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Insulin Resistance and Inflammation.International journal of molecular sciences · 2026
    Review
  7. Hypoxic adaptation theory of cancer.Frontiers in cell and developmental biology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. ATR-CHK1 Axis Inhibitors in Gastric Cancer Treatment.International journal of molecular sciences · 2025
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Oxidative Stress and Age-Related Tumors.Antioxidants (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jiawei ChenCollege of Letter and Science, University of California, Berkeley, CA 94720, USA.ORCID 0009-0005-3862-282X
Ravi PotlapalliCollege of Computing and Software Engineering, Kennesaw State University, Marietta, GA 30060, USA.
Heng QuanDepartment of Civil and Urban Engineering, New York University, New York, NY 11201, USA.
Lingtao ChenCollege of Computing and Software Engineering, Kennesaw State University, Marietta, GA 30060, USA.
Ying XieCollege of Computing and Software Engineering, Kennesaw State University, Marietta, GA 30060, USA.
Seyedamin PouriyehCollege of Computing and Software Engineering, Kennesaw State University, Marietta, GA 30060, USA.ORCID 0000-0002-5746-2914
Nazmus SakibCollege of Computing and Software Engineering, Kennesaw State University, Marietta, GA 30060, USA.
Lichao LiuStanford Cardiovascular Institute, Stanford University School of Medicine, Palo Alto, CA 94304, USA.
Yixin XieCollege of Computing and Software Engineering, Kennesaw State University, Marietta, GA 30060, USA.ORCID 0000-0002-4436-3474
Kennesaw State University · USBerkeley College · USNew York University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA damage is a critical factor contributing to genetic alterations, directly affecting human health, including developing diseases such as cancer and age-related disorders. DNA repair mechanisms play a pivotal role in safeguarding genetic integrity and preventing the onset of these ailments. Over the past decade, substantial progress and pivotal discoveries have been achieved in DNA damage and repair. This comprehensive review paper consolidates research efforts, focusing on DNA repair mechanisms, computational research methods, and associated databases. Our work is a valuable resource for scientists and researchers engaged in computational DNA research, offering the latest insights into DNA-related proteins, diseases, and cutting-edge methodologies. The review addresses key questions, including the major types of DNA damage, common DNA repair mechanisms, the availability of reliable databases for DNA damage and associated diseases, and the predominant computational research methods for enzymes involved in DNA damage and repair.

Indexed as

aging-related diseasescancercomputational biologyDNA damageDNA databaseDNA repair mechanismsuracil-DNA glycosylase

Identifiers

PMID38247733
PMCPMC10801582
OpenAlexW4390910841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.