ArticleAntibiotics (Basel, Switzerland)2024
CLSM-Guided Imaging for Quantifying Endodontic Disinfection.
Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 3 citations in OpenAlex.
- CLSM-guided imaging provides new insights into position-dependent limitations of endodontic disinfection.Clinical oral investigations · 2026Article
- Synthesis, Characterisation and Antibacterial Activity of Reduced Graphene Oxide-Cuprous Oxide Nanocomposite Against Dual Species Biofilms Using Clsm.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026Article
- Advances in oral disease models: a mini-review of developments from 2015 to 2025.Frontiers in dental medicine · 2026Review
- CLSM-Guided Imaging to Visualize the Depth of Effective Disinfection in Endodontics.Antibiotics (Basel, Switzerland) · 2025Article
- Multifunctional nano-delivery system based on DNase I and photodynamic therapy for combatting enterococcus faecalis biofilm infections.Scientific reports · 2025Article
- Comparison of a Novel Modality of Erbium-Doped Yttrium Aluminum Garnet Laser-Activated Irrigation and Ultrasonic Irrigation against MatureBioengineering (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Elimination of microbes in the root canal system is crucial for achieving long-term success in endodontic treatment. Further efforts in study design and standardization are needed in order to improve the validity and comparability of in vitro results on endodontic disinfection procedures, in turn improving clinical outcomes. This study optimizes two models at all steps: tooth selection, pretreatment, inoculation method (by growth or centrifugation), and confocal laser scanning microscopy (CLSM)-guided imaging of LIVE/DEAD-stained specimens. Individual anatomical conditions lead to substantial differences in penetration depth. Sclerosis grading (SCG), a classification system introduced in this study, provides information about the sclerosis status of the dentine and is helpful for careful, specific, and comparable tooth selection in in vitro studies. Sonically activated EDTA for the pretreatment of roots, inoculation of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.