Evidence map›Paper›PMID 38247570›Full record

ArticleAntibodies (Basel, Switzerland)2024

Clinical and Analytical Performance of ELISA Salivary Serologic Assay to Detect SARS-CoV-2 IgG in Children and Adults.

Andrea Padoan, Chiara Cosma, Costanza Di Chiara, Giulia Furlan, Stefano Gastaldo, Ilaria Talli, Daniele Donà, Daniela Basso, Carlo Giaquinto, Mario Plebani

Abstract read
In one paragraph

Article in Antibodies (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrea PadoanDepartment of Medicine (DIMED), University of Padova, 35128 Padova, Italy.
Chiara CosmaDepartment of Medicine (DIMED), University of Padova, 35128 Padova, Italy.
Costanza Di ChiaraDepartment of Women's and Children's Health, University of Padova, 35128 Padova, Italy.ORCID 0000-0002-3586-0612
Giulia FurlanQI.LAB.MED, Spin-off of the University of Padova, 35011 Padova, Italy.
Stefano GastaldoDepartment of Women's and Children's Health, University of Padova, 35128 Padova, Italy.
Ilaria TalliDepartment of Medicine (DIMED), University of Padova, 35128 Padova, Italy.ORCID 0000-0002-9425-6140
Daniele DonàDepartment of Women's and Children's Health, University of Padova, 35128 Padova, Italy.ORCID 0000-0001-7105-2105
Daniela BassoDepartment of Medicine (DIMED), University of Padova, 35128 Padova, Italy.ORCID 0000-0001-8745-6171
Carlo GiaquintoDepartment of Women's and Children's Health, University of Padova, 35128 Padova, Italy.
Mario PlebaniDepartment of Medicine (DIMED), University of Padova, 35128 Padova, Italy.ORCID 0000-0002-0270-1711

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Saliva is a promising matrix with several purposes. Our aim is to verify if salivary anti-SARS-CoV-2 antibody determination is suitable for monitoring immune responses. One hundred eighty-seven subjects were enrolled at University-Hospital Padova: 105 females (56.1%) and 82 males (43.9%), 95 (50.8%) children and 92 (49.2%) adults. Subjects self-collected saliva using Salivette; nineteen subjects collected three different samples within the day. A serum sample was obtained for all individuals. The N/S anti-SARS-CoV-2 salivary IgG (sal-IgG) and serum anti-SARS-CoV-2 S-RBD IgG (ser-IgG) were used for determining anti-SARS-CoV-2 antibodies. The mean (min-max) age was 9.0 (1-18) for children and 42.5 (20-61) for adults. Of 187 samples, 63 were negative for sal-IgG (33.7%), while 7 were negative for ser-IgG (3.7%). Spearman's correlation was 0.56 (

Indexed as

adultschildrenELISAsalivary samplesSARS-CoV-2 antibodies

Identifiers

PMID38247570
PMCPMC10801479

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.