Evidence map›Paper›PMID 38247501›Full record

ArticleAntioxidants (Basel, Switzerland)2024

Olive Leaf Extracts from Three Italian Olive Cultivars Exposed to Drought Stress Differentially Protect Cells against Oxidative Stress.

Luca Cerri, Sara Parri, Maria Celeste Dias, Angela Fabiano, Marco Romi, Giampiero Cai, Claudio Cantini, Ylenia Zambito

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. An Integrated Approach to Evaluate the Influence of DietaryAnimals : an open access journal from MDPI · 2026
    Article
  2. Review
  3. Potential Rapid Quantification of Antioxidant Capacity ofAntioxidants (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Luca CerriDepartment of Pharmacy, University of Pisa, Via Bonanno 33, 56126 Pisa, Italy.ORCID 0000-0003-3624-2215
Sara ParriDepartment of Life Sciences, University of Siena, Via Mattioli 4, 53100 Siena, Italy.ORCID 0000-0003-1589-9074
Maria Celeste DiasCentre for Functional Ecology, Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000-456 Coimbra, Portugal.ORCID 0000-0002-3083-6218
Angela FabianoDepartment of Pharmacy, University of Pisa, Via Bonanno 33, 56126 Pisa, Italy.ORCID 0000-0003-3912-840X
Marco RomiDepartment of Life Sciences, University of Siena, Via Mattioli 4, 53100 Siena, Italy.
Giampiero CaiDepartment of Life Sciences, University of Siena, Via Mattioli 4, 53100 Siena, Italy.ORCID 0000-0002-4511-3557
Claudio CantiniInstitute for BioEconomy (IBE), National Research Council (CNR), Strada Provinciale Aurelia Vecchia 49, 58022 Follonica, Italy.ORCID 0000-0002-0938-6013
Ylenia ZambitoDepartment of Pharmacy, University of Pisa, Via Bonanno 33, 56126 Pisa, Italy.ORCID 0000-0003-0064-233X
University of Siena · ITUniversity of Pisa · ITNational Research Council · ITUniversity of Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Olive leaves are an abundant by-product of olive oil production. Olive leaf extracts (OLEs) are rich in polyphenols, which can be used for health benefits. As polyphenols are the main antioxidant molecules in plants, plants typically increase their polyphenol content when exposed to drought stress. However, the phenolic profile of OLEs can vary in relation to the origin and variety of the plant material. In this work, olive leaf extracts from three different Italian olive cultivars (Giarraffa, Leccino, and Maurino) both exposed and not exposed to drought stress were studied in terms of antioxidant properties and profile, intestinal permeation, and protection against oxidative stress of human umbilical vein endothelial cells (HUVECs), since HUVECs are considered a model to study a wide range of diseases. OLEs from stressed Maurino and Giarraffa plants showed the highest increase in antioxidant capacity compared to controls. The phenolic profile of Maurino' was mainly increased by water deficit, with a large increase in the compounds oleuropein and luteolin-7-

Indexed as

antioxidantsdrought stressHUVECsOLEoleuropeinpolyphenols

Identifiers

PMID38247501
PMCPMC10812426
OpenAlexW4390662217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.