Evidence map›Paper›PMID 38247499›Full record

ArticleAntioxidants (Basel, Switzerland)2024

Antioxidant and Anti-Inflammatory Properties of Quail Yolk Oil via Upregulation of Superoxide Dismutase 1 and Catalase Genes and Downregulation of EIGER and Unpaired 2 Genes in a

Muhammad Sani Ismaila, Kamaldeen Olalekan Sanusi, Uwaisu Iliyasu, Mustapha Umar Imam, Karla Georges, Venkatesan Sundaram, Kegan Romelle Jones

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
4.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Muhammad Sani IsmailaDepartment of Basic Veterinary Sciences, School of Veterinary Medicine, The University of the West Indies, St. Augustine 999183, Trinidad and Tobago.ORCID 0000-0003-0266-8074
Kamaldeen Olalekan SanusiCentre for Advanced Medical Research and Training (CAMRET), Usmanu Danfodiyo University, Sokoto 840004, Nigeria.ORCID 0000-0002-9588-7710
Uwaisu IliyasuDepartment of Pharmacognosy and Drug Development, Faculty of Pharmaceutical Sciences, Kaduna State University, Kaduna 800283, Nigeria.
Mustapha Umar ImamCentre for Advanced Medical Research and Training (CAMRET), Usmanu Danfodiyo University, Sokoto 840004, Nigeria.ORCID 0000-0001-9888-4809
Karla GeorgesDepartment of Basic Veterinary Sciences, School of Veterinary Medicine, The University of the West Indies, St. Augustine 999183, Trinidad and Tobago.ORCID 0000-0001-5910-1429
Venkatesan SundaramDepartment of Basic Veterinary Sciences, School of Veterinary Medicine, The University of the West Indies, St. Augustine 999183, Trinidad and Tobago.ORCID 0000-0002-7665-2836
Kegan Romelle JonesDepartment of Basic Veterinary Sciences, School of Veterinary Medicine, The University of the West Indies, St. Augustine 999183, Trinidad and Tobago.ORCID 0000-0002-1260-7606
University of the West Indies · TTUsmanu Danfodiyo University · NGKaduna State University · NG

Funding

UWI, CAMRET grant number JMS 2111 and J2101309
6 · The paper itself

Abstract

Quail egg yolk oil (QEYO) has a rich history of medicinal use, showcasing heightened antioxidant and bioactive properties in our prior studies. This positions QEYO as a promising candidate for therapeutic and cosmetic applications. In this investigation, QEYO was extracted using ethanol/chloroform and 2-propanol/hexane solvents. GC-MS and FTIR analyses quantified 14 major bioactive compounds in the ethanol/chloroform fraction and 12 in the 2-propanol/hexane fraction. Toxicity evaluations in fruit flies, spanning acute, sub chronic, and chronic exposures, revealed no adverse effects. Negative geotaxis assays assessed locomotor activity, while biochemical assays using fly hemolymph gauged antioxidant responses. Real-time PCR revealed the relative expression levels of the antioxidant and anti-inflammatory genes. FTIR spectra indicated diverse functional groups, and the GC-MS results associated bioactive compounds with the regulation of the anti-inflammatory genes

Indexed as

antioxidant effectsEIGER and UPD2 gene down-regulationfruit flyFTIRGC–MSquail egg oil extracts

Identifiers

PMID38247499
PMCPMC10812611
OpenAlexW4390616633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.