Evidence map›Paper›PMID 38247484›Full record

ArticleAntioxidants (Basel, Switzerland)2023

A Metabolomic Signature of Ischemic Stroke Showing Acute Oxidative and Energetic Stress.

Moustapha Djite, Juan Manuel Chao de la Barca, Cinzia Bocca, Ndiaga Matar Gaye, Néné Oumou Kesso Barry, Mame Ndoumbé Mbacke, Ousmane Cissé, Pape Matar Kandji, Ndèye Marème Thioune, Najah Fatou Coly-Gueye and 7 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Moustapha DjiteLaboratoire de Biochimie Pharmaceutique, Faculté de Médecine, Pharmacie, Université Cheikh Anta Diop, Dakar 2238, Senegal.
Juan Manuel Chao de la BarcaDépartement de Biochimie et Biologie Moléculaire, Centre Hospitalier Universitaire (CHU), 49933 Angers, France.
Cinzia BoccaDépartement de Biochimie et Biologie Moléculaire, Centre Hospitalier Universitaire (CHU), 49933 Angers, France.
Ndiaga Matar GayeClinique Neurologique, Centre Hospitalier National Universitaire (CHNU) de FANN, Dakar 45701, Senegal.
Néné Oumou Kesso BarryLaboratoire de Biochimie Pharmaceutique, Faculté de Médecine, Pharmacie, Université Cheikh Anta Diop, Dakar 2238, Senegal.
Mame Ndoumbé MbackeLaboratoire de Biochimie, Centre Hospitalier National Universitaire (CHNU) de FANN, Dakar 45701, Senegal.
Ousmane CisséClinique Neurologique, Centre Hospitalier National Universitaire (CHNU) de FANN, Dakar 45701, Senegal.
Pape Matar KandjiLaboratoire de Biochimie, Centre Hospitalier National Universitaire (CHNU) de FANN, Dakar 45701, Senegal.
Ndèye Marème ThiouneLaboratoire de Biochimie, Centre Hospitalier National Universitaire (CHNU) de FANN, Dakar 45701, Senegal.
Najah Fatou Coly-GueyeHôpital Pour Enfants de Diamniadio, Dakar 10700, Senegal.
El Hadji Malick NdourLaboratoire de Biochimie Pharmaceutique, Faculté de Médecine, Pharmacie, Université Cheikh Anta Diop, Dakar 2238, Senegal.ORCID 0000-0002-0290-8675
Fatou Gueye-TallLaboratoire de Biochimie Pharmaceutique, Faculté de Médecine, Pharmacie, Université Cheikh Anta Diop, Dakar 2238, Senegal.
Amadou Gallo DiopClinique Neurologique, Centre Hospitalier National Universitaire (CHNU) de FANN, Dakar 45701, Senegal.
Gilles SimardDépartement de Biochimie et Biologie Moléculaire, Centre Hospitalier Universitaire (CHU), 49933 Angers, France.
Delphine Mirebeau-PrunierDépartement de Biochimie et Biologie Moléculaire, Centre Hospitalier Universitaire (CHU), 49933 Angers, France.
Papa Madieye GueyeLaboratoire de Biochimie Pharmaceutique, Faculté de Médecine, Pharmacie, Université Cheikh Anta Diop, Dakar 2238, Senegal.
Pascal ReynierDépartement de Biochimie et Biologie Moléculaire, Centre Hospitalier Universitaire (CHU), 49933 Angers, France.ORCID 0000-0003-0802-4608
Centre Hospitalier National Universitaire de Fann · SNCentre National de la Recherche Scientifique · FRCheikh Anta Diop University · SNCentre Hospitalier Universitaire d'Angers · FRHôpital Principal de Dakar · SN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolomics is a powerful data-driven tool for in-depth biological phenotyping that could help identify the specific metabolic profile of cryptogenic strokes, for which no precise cause has been identified. We performed a targeted quantitative metabolomics study in West African patients who had recently suffered an ischemic stroke, which was either cryptogenic (

Indexed as

cryptogenic ischemic strokeenergetic metabolismlipidomicsmetabolomicsmitochondriaoxidative stressstroke

Identifiers

PMID38247484
PMCPMC10812657
OpenAlexW4390403875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.