Evidence map›Paper›PMID 38247470›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Fractionation of High-Value Compounds from Hops Using an Optimised Sequential Extraction Procedure.

Ana I Paniagua-García, David Ruano-Rosa, Rebeca Díez-Antolínez

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ana I Paniagua-GarcíaCentre of Biofuels and Bioproducts, Agricultural Technological Institute of Castilla y León, Villarejo de Órbigo, E-24358 León, Spain.ORCID 0000-0003-4083-271X
David Ruano-RosaAgricultural Technological Institute of Castilla y León, Ctra. De Burgos, Km 119, E-47071 Valladolid, Spain.
Rebeca Díez-AntolínezCentre of Biofuels and Bioproducts, Agricultural Technological Institute of Castilla y León, Villarejo de Órbigo, E-24358 León, Spain.ORCID 0000-0001-7604-1886

Funding

European Agricultural Funds for Rural Development (FEADER funds) AGRORECOVERYEuropean Union's Horizon 2020 Research and Innovation Programe LIGNICOAT project Grant number: 101023342
6 · The paper itself

Abstract

This study describes the development and optimisation of a process for the extraction and fractionation of high-value compounds from hops. Firstly, the efficacy of ten organic solvents was compared for performing the initial solid-liquid extraction of compounds from hop pellets with subsequent fractionation steps. A methanol-dichloromethane mixture was selected and the extraction variables were optimised in order to maximise the recovery of valuable hop compounds separated into different streams (α- and β-acids in soft resins, xanthohumol in hard resins, and phenolics in spent solids) after fractionation steps. The optimisation results showed that extraction of hop pellets performed at room temperature with 19.7% (

Indexed as

antioxidant activityhop bitter acidshopsphenolic compoundssequential extractionxanthohumol

Identifiers

PMID38247470
PMCPMC10812624

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.