Evidence map›Paper›PMID 38247452›Full record

ArticleAntioxidants (Basel, Switzerland)2023

A Zero-Valent Sulfur Transporter Helps Podophyllotoxin Uptake into Bacterial Cells in the Presence of CTAB.

Honglei Liu, Huiyuan Yu, Rui Gao, Fulin Ge, Rui Zhao, Xia Lu, Tianqi Wang, Huaiwei Liu, Chunyu Yang, Yongzhen Xia and 1 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Honglei LiuState Key Laboratory of Microbial Technology, Shandong University, 72 Binhai Road, Qingdao 266237, China.
Huiyuan YuState Key Laboratory of Microbial Technology, Shandong University, 72 Binhai Road, Qingdao 266237, China.
Rui GaoState Key Laboratory of Microbial Technology, Shandong University, 72 Binhai Road, Qingdao 266237, China.
Fulin GeState Key Laboratory of Microbial Technology, Shandong University, 72 Binhai Road, Qingdao 266237, China.
Rui ZhaoState Key Laboratory of Microbial Technology, Shandong University, 72 Binhai Road, Qingdao 266237, China.
Xia LuState Key Laboratory of Microbial Technology, Shandong University, 72 Binhai Road, Qingdao 266237, China.
Tianqi WangState Key Laboratory of Microbial Technology, Shandong University, 72 Binhai Road, Qingdao 266237, China.
Huaiwei LiuState Key Laboratory of Microbial Technology, Shandong University, 72 Binhai Road, Qingdao 266237, China.ORCID 0000-0002-0483-5318
Chunyu YangState Key Laboratory of Microbial Technology, Shandong University, 72 Binhai Road, Qingdao 266237, China.
Yongzhen XiaState Key Laboratory of Microbial Technology, Shandong University, 72 Binhai Road, Qingdao 266237, China.ORCID 0000-0001-9950-1910
Luying XunState Key Laboratory of Microbial Technology, Shandong University, 72 Binhai Road, Qingdao 266237, China.ORCID 0000-0002-5770-9016
Shandong University · CN

Funding

the national key research and development program of China 2021YFC2101500
6 · The paper itself

Abstract

Podophyllotoxin (PTOX) is naturally produced by the plant Podophyllum species. Some of its derivatives are anticancer drugs, which are produced mainly by using chemical semi-synthesis methods. Recombinant bacteria have great potential in large-scale production of the derivatives of PTOX. In addition to introducing the correct enzymes, the transportation of PTOX into the cells is an important factor, which limits its modification in the bacteria. Here, we improved the cellular uptake of PTOX into

Indexed as

podophyllotoxinredox oxidative stresssulfane sulfurYedE1E2zero-valent sulfur

Identifiers

PMID38247452
PMCPMC10812762
OpenAlexW4390111959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.