ArticleJournal of autism and developmental disorders2025
Similar Gap-Overlap Profiles in Children with Fragile X Syndrome and IQ-Matched Autism.
Article in Journal of autism and developmental disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- Development of attentional disengagement in typically developing children and children with elevated levels of attentional deficits.Experimental brain research · 2025Article
- Challenges with shifting, regardless of disengagement: attention mechanisms and eye movements in Williams syndrome.Journal of neurodevelopmental disorders · 2025Article
- Heart rate defined sustained attention relates to visual attention in autism and fragile X syndrome.Scientific reports · 2025Article
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
purposeFragile X syndrome (FXS) is a single-gene disorder characterized by moderate to severe cognitive impairment and a high association with autism spectrum disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD). Atypical visual attention is a feature of FXS, ASD, and ADHD. Thus, studying early attentional patterns in young children with FXS can offer insight into early emerging neurocognitive processes underlying challenges and contribute to our understanding of common and unique features of ASD and ADHD in FXS.
methodsThe present study examined visual attention indexed by the gap-overlap paradigm in children with FXS (n = 39) compared to children with ASD matched on intellectual ability and age (n = 40) and age-matched neurotypical controls (n = 34). The relationship between gap-overlap performance and intellectual ability, ASD, and ADHD across groups was characterized. Saccadic reaction times (RT) were collected across baseline, gap, and overlap conditions.
resultsResults indicate no group differences in RT for any conditions. However, RT of the ASD and NT groups became slower throughout the experiment whereas RT of the FXS group did not change, suggesting difficulties in habituation for the FXS group. There was no relationship between RT and intellectual ability, ADHD, or ASD symptoms in the FXS and ASD groups. In the NT group, slower RT was related to elevated ADHD symptoms only.
conclusionTaken together, findings suggest that the social attention differences documented in FXS and ASD may be due to other cognitive factors, such as reward or motivation, rather than oculomotor control of visual attention.
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