Evidence map›Paper›PMID 38246906›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2024

A machine learning approach to differentiate wide QRS tachycardia: distinguishing ventricular tachycardia from supraventricular tachycardia.

Zhen-Zhen Li, Wei Zhao, YangMing Mao, Dan Bo, QiuShi Chen, Pipin Kojodjojo, FengXiang Zhang

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Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Zhen-Zhen Li *Section of Pacing and Electrophysiology, Division of Cardiology, First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing, 210006, Jiangsu, China.
Wei Zhao *Section of Pacing and Electrophysiology, Division of Cardiology, First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing, 210006, Jiangsu, China.
YangMing MaoSection of Pacing and Electrophysiology, Division of Cardiology, First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing, 210006, Jiangsu, China.
Dan BoSection of Pacing and Electrophysiology, Division of Cardiology, First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing, 210006, Jiangsu, China.
QiuShi ChenSection of Pacing and Electrophysiology, Division of Cardiology, First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing, 210006, Jiangsu, China.
Pipin KojodjojoHeart Center, National University, Singapore, Singapore.
FengXiang ZhangSection of Pacing and Electrophysiology, Division of Cardiology, First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing, 210006, Jiangsu, China. njzfx6@njmu.edu.cn.
Jiangsu Province Hospital · CNNanjing Medical University · CNNational University Heart Centre Singapore · SGSecond Affiliated Hospital of Nanjing Medical University · CN

Funding

Project 333 of Jiangsu Province 2022-2-408
6 · The paper itself

Abstract

backgroundDifferential diagnosis of wide QRS tachycardia (WQCT) has been a challenging issue. Published algorithms to distinguish ventricular tachycardia (VT) and supraventricular tachycardia (SVT) have limited diagnostic capabilities.

methodsA total of 278 patients with WQCT from January 2010 to March 2022 were enrolled. The electrophysiological study confirmed SVT in 154 patients and VT in 65 ones. Two hundred nineteen WQCT 12-lead ECGs were randomly divided into development cohort (n = 165) and testing cohort (n = 54) data sets. The development cohort was split into a training group (n = 115) and an internal validation group (n = 50). Forty ECG features extracted from the 219 WQCT ECGs are fed into 9 iteratively trained ML algorithms. This novel ML algorithm was also compared with four published algorithms.

resultsIn the development cohort, the Gradient Boosting Machine (GBM) model displayed the maximum area under curve (AUC) (0.91, 95% confidence interval (CI) 0.81-1.00). In the testing cohort, the GBM model had a higher AUC of 0.97 compared to 4 validated ECG algorithms, namely, Brugada (0.68), avR (0.62), RWPTII (0.72), and LLA algorithms (0.70). Accuracy, sensitivity, specificity, negative predictive value, and positive predictive value of the GBM model were 0.94, 0.97, 0.90, 0.94, and 0.95, respectively.

conclusionsA GBM ML model contributes to distinguishing SVT from VT based on surface ECG features. In addition, we were able to identify important indicators for distinguishing WQCT.

Indexed as

ElectrocardiographyMachine LearningTachycardia, SupraventricularTachycardia, VentricularAdultAgedAlgorithmsDiagnosis, DifferentialFemaleHumansMaleMiddle AgedElectrocardiogram (ECG)Machine learning (ML)Wide QRS complex tachycardia (WQCT)

Identifiers

PMID38246906
OpenAlexW4391074025

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.