Evidence map›Paper›PMID 38246829›Full record

ArticleInternational dental journal2024

COVID-19 Severity in Patients With Apical Periodontitis: A Case Control Study.

Nadya Marouf, Raidan Ba-Hattab, Fatima Al-Sheeb, Amal Diab, Hanan Diab, Maryam Al-Majed, Khalid Al-Haithami, Ghanim Al-Mannai, Noha Barhom, Shailaja Tharupeedikayil and 1 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International dental journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Nadya MaroufDivision of Endodontics, Department of Dentistry, Oral Health Institute, Hamad Medical Corporation, Doha, Qatar; College of Dental Medicine, QU Health, Qatar University, Doha, Qatar; Hamad Dental Center, Hamad Medical Corporation, Doha, Qatar.
Raidan Ba-HattabCollege of Dental Medicine, QU Health, Qatar University, Doha, Qatar.
Fatima Al-SheebDivision of Endodontics, Department of Dentistry, Oral Health Institute, Hamad Medical Corporation, Doha, Qatar; College of Dental Medicine, QU Health, Qatar University, Doha, Qatar; Hamad Dental Center, Hamad Medical Corporation, Doha, Qatar.
Amal DiabDivision of Endodontics, Department of Dentistry, Oral Health Institute, Hamad Medical Corporation, Doha, Qatar; College of Dental Medicine, QU Health, Qatar University, Doha, Qatar.
Hanan DiabDivision of Endodontics, Department of Dentistry, Oral Health Institute, Hamad Medical Corporation, Doha, Qatar; College of Dental Medicine, QU Health, Qatar University, Doha, Qatar.
Maryam Al-MajedDivision of Endodontics, Department of Dentistry, Oral Health Institute, Hamad Medical Corporation, Doha, Qatar; College of Dental Medicine, QU Health, Qatar University, Doha, Qatar.
Khalid Al-HaithamiDivision of Endodontics, Department of Dentistry, Oral Health Institute, Hamad Medical Corporation, Doha, Qatar; Hamad Dental Center, Hamad Medical Corporation, Doha, Qatar.
Ghanim Al-MannaiDivision of Endodontics, Department of Dentistry, Oral Health Institute, Hamad Medical Corporation, Doha, Qatar; College of Dental Medicine, QU Health, Qatar University, Doha, Qatar; Hamad Dental Center, Hamad Medical Corporation, Doha, Qatar.
Noha BarhomCollege of Dental Medicine, QU Health, Qatar University, Doha, Qatar.
Shailaja TharupeedikayilCollege of Dental Medicine, QU Health, Qatar University, Doha, Qatar; Hamad Dental Center, Hamad Medical Corporation, Doha, Qatar.
Faleh TamimiCollege of Dental Medicine, QU Health, Qatar University, Doha, Qatar. Electronic address: fmarino@qu.edu.qa.
Hamad Medical Corporation · QAQatar University · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesApical periodontitis (AP) has been associated with systemic inflammatory biomarkers that have also been associated with COVID-19 severity. This study was designed to test the hypothesis that the presence of apical periodontitis could be associated with increased risk of COVID-19 complications.

methodsA case control study (N = 949) was performed using the medical and dental records of patients diagnosed with COVID-19 in the State of Qatar between March 2020 and February 2021. Cases comprised COVID-19 patients (n = 63) who experienced complications (death, intensive care unit admissions, mechanical ventilation), and controls were COVID-19 patients (n = 886) who recovered without such complications. The presence of periapical apical periodontitis was assessed on the radiographic records taken prior to COVID-19 infection. Associations between apical periodontitis and COVID 19 complications were analysed using logistic regression models adjusted for demographic and medical factors. Blood biomarkers were assessed in both groups and compared using the Kruskal-Wallis test.

resultsCOVID-19 complications were found to be associated with the presence of apical periodontitis (adjusted odds ratio = 2.72; 95% CI, 1.30-5.68; P = .008). Blood analyses revealed that COVID-19 patients with apical periodontitis had higher levels of white blood cells and haemoglobin A1c than the patients without apical periodontitis.

conclusionsThe presence of apical periodontitis could be associated with increased risk of COVID-19 complications.

Indexed as

COVID-19Periapical PeriodontitisSeverity of Illness IndexAdultBiomarkersCase-Control StudiesFemaleHumansMaleMiddle AgedQatarRespiration, ArtificialRisk FactorsSARS-CoV-2BiomarkersBiomarkersInflammationOral diseasesPeriapical diseasesRadiography panoramicSARS-CoV-2

Identifiers

PMID38246829
PMCPMC11287187
OpenAlexW4391057927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.