Evidence map›Paper›PMID 38245852›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2024

Geometric determinants of the mechanical behavior of image-based finite element models of the intervertebral disc.

Ingmar Fleps, Harrah R Newman, Dawn M Elliott, Elise F Morgan

Open access · bronzeAbstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ingmar FlepsBoston University, Boston, Massachusetts, USA.
Harrah R NewmanUniversity of Delaware, Newark, Delaware, USA.
Dawn M ElliottUniversity of Delaware, Newark, Delaware, USA.ORCID 0000-0003-4792-1029
Elise F MorganBoston University, Boston, Massachusetts, USA.ORCID 0000-0002-3994-1890
Boston University · USUniversity of Delaware · US

Funding

3-D Visualization and Prediction of Vertebral FracturesR01AR054620 · NIAMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI MORGAN, ELISE F · 2008 to 2025
$6.7M
Disc Mechanics and Altered Loading in DegenerationR01AR050052 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI ELLIOTT, DAWN M · 2005 to 2024
$4.7M
Non-Invasive Evaluation of In Vivo Intervertebral Disc Mechanical FunctionF31AR081687 · NIAMS · UNIVERSITY OF DELAWARE · PI NEWMAN, HARRAH · 2022 to 2024
$124k
NIAMS NIH HHS F31 AR081687NIAMS NIH HHS R01 AR050052NIAMS NIH HHS R01 AR054620NIH HHS F31 AR081687NIH HHS R01 AR054620
6 · The paper itself

Abstract

The intervertebral disc is an important structure for load transfer through the spine. Its injury and degeneration have been linked to pain and spinal fractures. Disc injury and spine fractures are associated with high stresses; however, these stresses cannot be measured, necessitating the use of finite element (FE) models. These models should include the disc's complex structure, as changes in disc geometry have been linked to altered mechanical behavior. However, image-based models using disc-specific structures have yet to be established. This study describes a multiphasic FE modeling approach for noninvasive estimates of subject-specific intervertebral disc mechanical behavior based on medical imaging. The models (n = 22) were used to study the influence of disc geometry on the predicted global mechanical response (moments and forces), internal local disc stresses, and tractions at the interface between the disc and the bone. Disc geometry was found to have a strong influence on the predicted moments and forces on the disc (R

Indexed as

Finite Element AnalysisIntervertebral DiscAdultBiomechanical PhenomenaFemaleHumansLumbar VertebraeMaleMiddle AgedModels, BiologicalStress, Mechanicalbiomechanicsfinite element analysisintervertebral discmodelingspine

Identifiers

PMID38245852
PMCPMC11055679
OpenAlexW4391065966

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.