Evidence map›Paper›PMID 38245799›Full record

ArticleJournal of cardiothoracic surgery2024

Efficacy and safety of intraoperative partial spray of 50% glucose for patients with spontaneous pneumothorax.

Ryota Kiriyama, Shota Nakamura, Hironori Oyamatsu, Seijiro Niimi, Takaki Fujimura, Takehiko Okagawa, Toyofumi Fengshi Chen-Yoshikawa

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiothoracic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ryota KiriyamaDepartment of Thoracic Surgery, Okazaki City Hospital, 3-1 Gosyoai, Koryuji-cho, Okazaki, 444-8553, Japan.
Shota NakamuraDepartment of Thoracic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. shota197065@med.nagoya-u.ac.jp.
Hironori OyamatsuDepartment of Thoracic Surgery, Okazaki City Hospital, 3-1 Gosyoai, Koryuji-cho, Okazaki, 444-8553, Japan.
Seijiro NiimiDepartment of Thoracic Surgery, Okazaki City Hospital, 3-1 Gosyoai, Koryuji-cho, Okazaki, 444-8553, Japan.
Takaki FujimuraDepartment of Thoracic Surgery, Okazaki City Hospital, 3-1 Gosyoai, Koryuji-cho, Okazaki, 444-8553, Japan.
Takehiko OkagawaDepartment of Thoracic Surgery, Okazaki City Hospital, 3-1 Gosyoai, Koryuji-cho, Okazaki, 444-8553, Japan.
Toyofumi Fengshi Chen-YoshikawaDepartment of Thoracic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Okazaki City Hospital · JPNagoya University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe management for pneumothorax patients involves surgical intervention, nevertheless postoperative recurrences are often encountered. To reduce the rates of recurrence, thoracic surgeons have experimented with various novel techniques, such as pleural abrasion, chemical pleurodesis, and staple line coverage with absorbable sheets, in addition to bullectomy. And in recent years, there have been reports of the effectiveness of the use of intraoperative glucose intrapleural spray (GIS) containing 50 ml of 50% glucose solution in addition to bullectomy. However, information on the effects and adverse events of GIS is limited. Current study was aimed to assess the efficacy and safety of GIS in preventing recurrence of pneumothorax. PATIENTS AND

methodsWe conducted a retrospective study with 74 cases of bullectomy with or without GIS between 2018 and 2021 at Okazaki City Hospital. Of these cases, 50 received GIS (GIS group) while 24 were treated conservatively (C group).

resultThe GIS group consisted of 46 males and 4 females, whereas the C group consisted of 23 males and 1 female, with mean ages of 38.5 ± 5.7 years and 30.5 ± 6.7 years, respectively. The GIS group exhibited a mean increase in blood glucose of 23.8 mg/dL postoperatively, and postoperative infections were observed in 2 cases in the GIS group (4.0%) and 2 cases in the C group (8.3%). The NRS scores of the patients in the GIS group and the C group three hours postoperatively were 4.0 and 3.1, respectively (p = 0.28). No prolongation of postoperative drainage period by GIS was observed (1.2 days and 1.4 days in the GIS and C groups, respectively). Postoperative recurrence occurred in two patients from the C group. The postoperative total drainage volumes were 341.8 ± 25.2 ml and 74.2 ± 25.5 ml in the GIS and C groups, respectively, showing a significant increase in drainage volume (p < 0.01). None of them presented dehydration-related symptoms.

conclusionsThe use of intraoperative glucose intrapleural spray is effective and safe in terms of preventing recurrences and postoperative complications.

Indexed as

PneumothoraxAdultFemaleGlucoseHumansMalePleurodesisPostoperative ComplicationsRecurrenceRetrospective StudiesThoracic Surgery, Video-AssistedTreatment OutcomeGlucose50% Glucose solutionBullectomyPleurodesisPneumothoraxVideo-assisted thoracic surgery (VATS)

Identifiers

PMID38245799
PMCPMC10799354
OpenAlexW4391051997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.