Observational studyBMC musculoskeletal disorders2024
The impact of primary total hip and knee replacement on frailty: an observational prospective analysis.
Observational study in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Frailty and Sarcopenia as Predictors of Functional Recovery After Total Hip and Knee Arthroplasty: A Narrative Review.Journal of clinical medicine · 2026Review
- Exploratory analysis of depressive symptom trajectories before and after hip or knee arthroplasty in geriatric patients.Archives of orthopaedic and trauma surgery · 2026Article
- Trajectory of test components of a comprehensive geriatric assessment in orthogeriatric patients following total hip and knee arthroplasty.BMC geriatrics · 2026Article
- Total hip arthroplasty restores population health-related quality of life norms : a propensity-matched study with mediation analysis of BMI.Bone & joint open · 2026Article
- Intensive care needs after hip and knee replacement: understanding risk profiles for severe postoperative complications.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025Article
- Frailty and associated healthcare expenditures among patients undergoing total hip and knee arthroplasty.The Journal of frailty & aging · 2025Article
- Clinical frailty scale predicts outcomes following total joint arthroplasty.Arthroplasty (London, England) · 2025Article
- Influence of parkinson's disease on complications and revisions in total hip and knee arthroplasty: insights from a matched pair analysis.International orthopaedics · 2025Article
- Impressive Short-Term Improvement in Functional Outcome and Quality of Life after Primary Total Hip Arthroplasty (THA) in the Orthogeriatric Patient in a Prospective Monocentric Trial.Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOsteoarthritis is a prevalent condition in frail older adults that requires hip or knee replacement in many patients. The aim of the study was to determine the impact of hip and knee arthroplasty on frailty.
methodsIn this prospective short-term study, we used data from 101 participants of the ongoing Special Orthopaedic Geriatrics (SOG) trial, funded by the German Federal Joint Committee (GBA). Frailty, measured by Fried's Physical Frailty Phenotype (PFP), was assessed preoperatively, 7 days postoperatively, 4-6 weeks and 3 months after hip and knee arthroplasty. ANOVA with repeated measures and post-hoc tests for the subgroups were used for the statistical analysis.
resultsOf the 101 participants, 50 were pre-frail (1-2 PFP criteria) and 51 were frail (≥ 3 PFP criteria) preoperatively. In the pre-frail group, the PFP score decreased from 1.56 ± 0.50 (median 2) preoperatively to 0.53 ± 0.73 (median 0) 3 months after surgery (p < 0.001). The PFP score in the frail cohort decreased from 3.39 ± 1.45 (median 3) preoperatively to 1.27 ± 1.14 (median 1) 3 months postoperatively (p < 0.001). While the PFP score of the pre-frail participants increased 7 days after surgery, the PFP score of the frail group decreased significantly.
conclusionPre-frail individuals often regain robustness and patients with frailty are no longer assessed as frail after surgery. Joint replacement is an effective intervention to improve frailty in hip and knee osteoarthritis.
trial registrationThis study is part of the Special Orthopaedic Geriatrics (SOG) trial, German Clinical Trials Register DRKS00024102. Registered on 19 January 2021.
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