Evidence map›Paper›PMID 38245578›Full record

ArticleScientific reports2024

Revealing the mechanistic interactions of profenofos and captan pesticides with serum protein via biophysical and computational investigations.

Kamonrat Phopin, Waralee Ruankham, Supaluk Prachayasittikul, Virapong Prachayasittikul, Tanawut Tantimongcolwat

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kamonrat PhopinCenter for Research Innovation and Biomedical Informatics, Faculty of Medical Technology, Mahidol University, Bangkok, 10700, Thailand.
Waralee RuankhamCenter for Research Innovation and Biomedical Informatics, Faculty of Medical Technology, Mahidol University, Bangkok, 10700, Thailand.
Supaluk PrachayasittikulCenter for Research Innovation and Biomedical Informatics, Faculty of Medical Technology, Mahidol University, Bangkok, 10700, Thailand.
Virapong PrachayasittikulDepartment of Clinical Microbiology and Applied Technology, Faculty of Medical Technology, Mahidol University, Bangkok, 10700, Thailand.
Tanawut TantimongcolwatCenter for Research Innovation and Biomedical Informatics, Faculty of Medical Technology, Mahidol University, Bangkok, 10700, Thailand. tanawut.tan@mahidol.ac.th.
Mahidol University · TH

Funding

Mahidol University Basic Research Fund: fiscal year 2022National Research Council of Thailand (NRCT) and Mahidol University NRCT5-RSA63015-25
6 · The paper itself

Abstract

Profenofos (PF) and captan (CT) are among the most utilized organophosphorus insecticides and phthalimide fungicides, respectively. To elucidate the physicochemical and influential toxicokinetic factors, the mechanistic interactions of serum albumin and either PF or CT were carried out in the current study using a series of spectroscopy and computational analyses. Both PF and CT could bind to bovine serum albumin (BSA), a representative serum protein, with moderate binding constants in a range of 10

Indexed as

CaptanOrganothiophosphatesPesticidesBinding SitesCircular DichroismMolecular Docking SimulationProtein BindingSerum AlbuminSerum Albumin, BovineSpectrometry, FluorescenceThermodynamicsCaptanOrganothiophosphatesPesticidesprofenofosSerum AlbuminSerum Albumin, Bovine

Identifiers

PMID38245578
PMCPMC10799918
OpenAlexW4391052796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.