ArticleNature communications2024
Interindividual- and blood-correlated sweat phenylalanine multimodal analytical biochips for tracking exercise metabolism.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Continuous Molecular Monitoring Using Electrochemical Aptamer-Based Sensors: Remaining Challenges for Long-Term In Vivo Deployment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Advances and Challenges in Wearable Sensors for Health Monitoring.ACS applied materials & interfaces · 2026Review
- Self-powered intelligence for personalized healthcare.National science review · 2026Review
- Amphibian-inspired neuromorphic dynamic vision systems based on ferroelectric field-effect transistor.Nature communications · 2026Article
- Real-time nanomolar vitamin monitoring in sweat using an electrochemical skin-attached device.Nature communications · 2026Article
- A wireless sweat sensing with a pH-based correlation model for continuous glucose monitoring and diabetes management during exercise.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Review
- Smart microfluidic devices integrated in electrochemical point-of-care platforms for biomarker detection in biological fluids.Analytical and bioanalytical chemistry · 2026Review
- pH calibration allows accurate glucose detection in interstitial fluid via reverse iontophoresis.Nature communications · 2025Article
- Seeing inside the Body Using Wearable Sensing and Imaging Technologies.Advanced healthcare materials · 2025Review
- A highly sensitive and multiplexed wireless sensing system with skin-like compliance and stretchability for wearable applications.Science advances · 2025Article
- Artificial Nervous Systems.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Eco-Friendly Conformal and Self-Adhesive Electrochemical Sensors for Sweat Monitoring.ACS applied materials & interfaces · 2025Article
- Temperature Abetted Synthesis of Zeolitic Imidazolate Framework-Derived 3D Zn@N-C with MXene and Gold Nanostars-Based Immunosensor for the Detection of Prostate-Specific Antigen.ACS applied materials & interfaces · 2025Article
- The Utility of Fourier Transform Infrared Spectroscopy (FTIR) for Detecting Exercise-Induced Changes in the Human Hand Epidermis.Journal of biophotonics · 2025Article
- All-flexible chronoepifluidic nanoplasmonic patch for label-free metabolite profiling in sweat.Nature communications · 2025Article
- Noninvasive On-Skin Biosensors for Monitoring Diabetes Mellitus.Nano-micro letters · 2025Review
- Cellulose Nanocrystals for Advanced Optics and Electronics: Current Status and Future Directions.Micromachines · 2025Article
- From Lab to Life: Self-Powered Sweat Sensors and Their Future in Personal Health Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- The molecular signature of heat stress in sweat reveals non-invasive biomarker candidates for health monitoring.Communications biology · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
In situ monitoring of endogenous amino acid loss through sweat can provide physiological insights into health and metabolism. However, existing amino acid biosensors are unable to quantitatively assess metabolic status during exercise and are rarely used to establish blood-sweat correlations because they only detect a single concentration indicator and disregard sweat rate. Here, we present a wearable multimodal biochip integrated with advanced electrochemical electrodes and multipurpose microfluidic channels that enables simultaneous quantification of multiple sweat indicators, including phenylalanine and chloride, as well as sweat rate. This combined measurement approach reveals a negative correlation between sweat phenylalanine levels and sweat rates among individuals, which further enables identification of individuals at high metabolic risk. By tracking phenylalanine fluctuations induced by protein intake during exercise and normalizing the concentration indicator by sweat rates to reduce interindividual variability, we demonstrate a reliable method to correlate and analyze sweat-blood phenylalanine levels for personal health monitoring.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.