Evidence map›Paper›PMID 38244931›Full record

ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2024

Layer-specific fast strain-encoded cardiac magnetic resonance imaging aids in the identification and discrimination of acute myocardial injury: a prospective proof-of-concept study.

Lukas D Weberling, David Albert, Andreas Ochs, Marco Ochs, Deborah Siry, Janek Salatzki, Evangelos Giannitsis, Norbert Frey, Johannes Riffel, Florian André

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Layer-specific fast strain-encoded cardiovascular magnetic resonance in suspected acute coronary syndrome: a prospective study.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Lukas D WeberlingDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany; DZHK (German Centre for Cardiovascular Research), Heidelberg, Germany. Electronic address: Lukas.Weberling@Med.Uni-Heidelberg.de.
David AlbertDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany.
Andreas OchsDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany; DZHK (German Centre for Cardiovascular Research), Heidelberg, Germany.
Marco OchsDepartment of Cardiology, Angiology, Frankfurt University Hospital, Frankfurt am Main, Germany; Faculty of Medicine, University of Heidelberg, Heidelberg, Germany.
Deborah SiryDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany.
Janek SalatzkiDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany; DZHK (German Centre for Cardiovascular Research), Heidelberg, Germany.
Evangelos GiannitsisDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany; DZHK (German Centre for Cardiovascular Research), Heidelberg, Germany.
Norbert FreyDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany; DZHK (German Centre for Cardiovascular Research), Heidelberg, Germany.
Johannes RiffelDepartment of Cardiology and Angiology, Robert-Bosch-Hospital, Stuttgart, Germany.
Florian AndréDepartment of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany; DZHK (German Centre for Cardiovascular Research), Heidelberg, Germany.
University Hospital Heidelberg · DEGerman Centre for Cardiovascular Research · DEHeidelberg University · DEGoethe University Frankfurt · DERobert Bosch Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute myocardial injury is a common diagnosis in the emergency department and differential diagnoses are numerous. Cardiac magnetic resonance (CMR) strain sequences, such as fast strain ENCoded (fSENC), are early predictors of myocardial function loss. This study assessed the potential diagnostic and prognostic benefits of a layer-specific approach.

methodsFor this prospective study, patients in the emergency department fulfilling rule-in criteria for non-ST-elevation myocardial infarction (NSTEMI) received an ultra-fast fSENC CMR. Volunteers without cardiac diseases (controls) were recruited for comparison. Measurements were performed in a single heartbeat acquisition to measure global longitudinal strain (GLS) and segmental longitudinal strain and dysfunctional segments. The GLS was measured in two layers and a difference (GLS

resultsA total of 114 participants, including 50 controls, were included. The 64 patients (51 male) were divided into a NSTEMI (25), myocarditis (16), and other myocardial injury group (23). GLS served as a potent predictor of myocardial injury (area under the curve (AUC) 91.8%). The GLS

conclusionsLayer-specific strain is a potential new marker with high diagnostic performance in the identification and differentiation of acute myocardial injuries.

Indexed as

Magnetic Resonance Imaging, CineNon-ST Elevated Myocardial InfarctionPredictive Value of TestsProof of Concept StudyAdultAgedBiomechanical PhenomenaCase-Control StudiesDiagnosis, DifferentialFemaleHeart RateHumansImage Interpretation, Computer-AssistedMaleMiddle AgedMyocardial ContractionCardiovascular ImagingCMRfSENCMyocarditisNSTEMIStrain

Identifiers

PMID38244931
PMCPMC11211227
OpenAlexW4391075290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.