Evidence map›Paper›PMID 38244135›Full record

ReviewWorld journal of urology2024

A review of stereotactic ablative radiotherapy for nonmetastatic renal cell carcinoma.

Osbert Zalay, Prateek Mehra, Ian Pereira, Julia Malone, Shawn Malone

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Osbert ZalayRadiation Oncology, Kingston Health Science Centre, Kingston, Canada.
Prateek MehraOttawa Hospital Cancer Centre, Ottawa Hospital Regional Cancer Program, Ottawa, Canada.
Ian PereiraRadiation Oncology, Kingston Health Science Centre, Kingston, Canada.
Julia MaloneOttawa Hospital Cancer Centre, Ottawa Hospital Regional Cancer Program, Ottawa, Canada.
Shawn MaloneOttawa Hospital Cancer Centre, Ottawa Hospital Regional Cancer Program, Ottawa, Canada. shawnmalone89@gmail.com.ORCID http://orcid.org/0000-0001-5497-3455
Ottawa Hospital · CAKingston Health Sciences Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal cell carcinoma (RCC) is an uncommon malignancy whose incidence has been increasing over the past few decades, posing treatment challenges for elderly or infirm patients who are not surgical candidates. Stereotactic ablative radiotherapy (SABR) has emerged as a promising non-invasive treatment modality for RCC. The high dose-per-fraction used in SABR overcomes some of the mechanisms of radioresistance that has hindered the effective treatment of RCC with conventional radiotherapy. For primary RCC, local control rates for SABR exceed 90%, with typically minimal grade 3 or higher toxicities, offering a viable alternative for inoperable patients and those not eligible for or unable to tolerate radiofrequency or cryotherapy ablation. SABR can also be used in patients with a solitary kidney as a strategy for renal preservation to avoid need for dialysis. Given its excellent local control rates, low toxicity and preservation of renal function, SABR offers an attractive alternative to more invasive modalities for treatment of localized RCC.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsRadiosurgeryAgedHumansKidneyTreatment OutcomeRenal cell cancerStereotactic body radiotherapy

Identifiers

PMID38244135
OpenAlexW4391051278

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.