Evidence map›Paper›PMID 38244046›Full record

ArticleEuropean radiology2024

MRI-based Neuropathy Score Reporting And Data System (NS-RADS): multi-institutional wider-experience usability study of peripheral neuropathy conditions among 32 radiology readers.

Avneesh Chhabra, Flavio Duarte Silva, Bayan Mogharrabi, Mina Guirguis, Oganes Ashikyan, Michael Rasper, Eunhae Park, Sven S Walter, Monica Umpierrez, Parham Pezeshk and 35 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

45 authors.

Avneesh ChhabraDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX, 75390-9178, USA. avneesh.chhabra@utsouthwestern.edu.ORCID http://orcid.org/0000-0002-0718-3802
Flavio Duarte SilvaDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX, 75390-9178, USA.
Bayan MogharrabiDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX, 75390-9178, USA.
Mina GuirguisDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX, 75390-9178, USA.
Oganes AshikyanDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX, 75390-9178, USA.
Michael RasperInstitute of Radiology, Cantonal Hospital Münsterlingen, Münsterlingen, Switzerland.
Eunhae ParkDivision of Musculoskeletal Radiology, Department of Radiology, NYU Grossman School of Medicine, New York City, NY, USA.
Sven S WalterDivision of Musculoskeletal Radiology, Department of Radiology, NYU Grossman School of Medicine, New York City, NY, USA.
Monica UmpierrezDivision of Musculoskeletal Radiology, Department of Radiology and Imaging Services, Emory University School of Medicine, Atlanta, GA, USA.
Parham PezeshkDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX, 75390-9178, USA.
Peter C ThurlowMusculoskeletal Imaging and Intervention, Department of Radiology, University of Washington, Seattle, WA, USA.
Akshaya JagadaleDepartment of Radiology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Gitanjali BajajDepartment of Radiology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Aparna KomarrajuDepartment of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Jim S WuDepartment of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Antonio AguileraDivision of Musculoskeletal Radiology, Department of Radiology, University of Miami Miller School of Medicine, Miami, FL, USA.
Fabiano Nassar CardosoDivision of Musculoskeletal Radiology, Department of Radiology, University of Miami Miller School of Medicine, Miami, FL, USA.
Felipe SouzaDivision of Musculoskeletal Radiology, Department of Radiology, University of Miami Miller School of Medicine, Miami, FL, USA.
SubbaRao ChagantiSomerset NHS Foundation Trust, Taunton, Somerset, UK.
Neha AntilDepartment of Radiology, Stanford University, Stanford, CA, USA.
Wilfred ManzanoDepartment of Radiology, Stanford University, Stanford, CA, USA.
Alexander StebnerInstitute of Radiology, Cantonal Hospital Münsterlingen, Münsterlingen, Switzerland.
Jochen EversInstitute of Radiology, Cantonal Hospital Münsterlingen, Münsterlingen, Switzerland.
Matthew PettersonDepartment of Radiology, Stanford University, Stanford, CA, USA.
Thomas GeisbushDepartment of Radiology, Stanford University, Stanford, CA, USA.
Chad DowningMusculoskeletal Imaging and Intervention, Department of Radiology, University of Washington, Seattle, WA, USA.
Diana ChristensenMusculoskeletal Imaging and Intervention, Department of Radiology, University of Washington, Seattle, WA, USA.
Elizabeth HorneberMusculoskeletal Imaging and Intervention, Department of Radiology, University of Washington, Seattle, WA, USA.
Jun Man KimDivision of Musculoskeletal Radiology, Department of Radiology and Imaging Services, Emory University School of Medicine, Atlanta, GA, USA.
Rangarajan PurushothamanDepartment of Radiology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Shilpa MohananDepartment of Radiology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Surbhi RaichandaniDepartment of Radiology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
George VilanilamDepartment of Radiology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Clementina CabreraDivision of Musculoskeletal Radiology, Department of Radiology, University of Miami Miller School of Medicine, Miami, FL, USA.
John ManovDivision of Musculoskeletal Radiology, Department of Radiology, University of Miami Miller School of Medicine, Miami, FL, USA.
Sean MaloneyDivision of Musculoskeletal Radiology, Department of Radiology, University of Miami Miller School of Medicine, Miami, FL, USA.
Swati D DeshmukhDepartment of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Amelie M LutzDivision of Musculoskeletal Radiology, Department of Radiology, NYU Grossman School of Medicine, New York City, NY, USA.
Jan FritzDivision of Musculoskeletal Radiology, Department of Radiology, NYU Grossman School of Medicine, New York City, NY, USA.
Gustav AndreisekInstitute of Radiology, Cantonal Hospital Münsterlingen, Münsterlingen, Switzerland.
Majid ChalianMusculoskeletal Imaging and Intervention, Department of Radiology, University of Washington, Seattle, WA, USA.
Philip K WongDivision of Musculoskeletal Radiology, Department of Radiology and Imaging Services, Emory University School of Medicine, Atlanta, GA, USA.
Tarun PandeyDepartment of Radiology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Ty SubhawongDivision of Musculoskeletal Radiology, Department of Radiology, University of Miami Miller School of Medicine, Miami, FL, USA.
Yin XiDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX, 75390-9178, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the inter-reader reliability and diagnostic performance of classification and severity scales of Neuropathy Score Reporting And Data System (NS-RADS) among readers of differing experience levels after limited teaching of the scoring system.

methodsThis is a multi-institutional, cross-sectional, retrospective study of MRI cases of proven peripheral neuropathy (PN) conditions. Thirty-two radiology readers with varying experience levels were recruited from different institutions. Each reader attended and received a structured presentation that described the NS-RADS classification system containing examples and reviewed published articles on this subject. The readers were then asked to perform NS-RADS scoring with recording of category, subcategory, and most likely diagnosis. Inter-reader agreements were evaluated by Conger's kappa and diagnostic accuracy was calculated for each reader as percent correct diagnosis. A linear mixed model was used to estimate and compare accuracy between trainees and attendings.

resultsAcross all readers, agreement was good for NS-RADS category and moderate for subcategory. Inter-reader agreement of trainees was comparable to attendings (0.65 vs 0.65). Reader accuracy for attendings was 75% (95% CI 73%, 77%), slightly higher than for trainees (71% (69%, 72%), p = 0.0006) for nerves and comparable for muscles (attendings, 87.5% (95% CI 86.1-88.8%) and trainees, 86.6% (95% CI 85.2-87.9%), p = 0.4). NS-RADS accuracy was also higher than average accuracy for the most plausible diagnosis for attending radiologists at 67% (95% CI 63%, 71%) and for trainees at 65% (95% CI 60%, 69%) (p = 0.036).

conclusionNon-expert radiologists interpreted PN conditions with good accuracy and moderate-to-good inter-reader reliability using the NS-RADS scoring system. CLINICAL RELEVANCE STATEMENT: The Neuropathy Score Reporting And Data System (NS-RADS) is an accurate and reliable MRI-based image scoring system for practical use for the diagnosis and grading of severity of peripheral neuromuscular disorders by both experienced and general radiologists. KEY POINTS: • The Neuropathy Score Reporting And Data System (NS-RADS) can be used effectively by non-expert radiologists to categorize peripheral neuropathy. • Across 32 different experience-level readers, the agreement was good for NS-RADS category and moderate for NS-RADS subcategory. • NS-RADS accuracy was higher than the average accuracy for the most plausible diagnosis for both attending radiologists and trainees (at 75%, 71% and 65%, 65%, respectively).

Indexed as

Magnetic Resonance ImagingObserver VariationPeripheral Nervous System DiseasesAdultAgedClinical CompetenceCross-Sectional StudiesFemaleHumansMaleMiddle AgedRadiologistsRadiologyReproducibility of ResultsRetrospective StudiesSeverity of Illness IndexEntrapment neuropathiesMagnetic resonance imagingPeripheral nerve injuryPeripheral nerve sheath tumorPeripheral neuropathy

Identifiers

PMID38244046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.