Evidence map›Paper›PMID 38243733›Full record

ArticleJournal of athletic training2024

Persistent Early Knee Osteoarthritis Symptoms From 6 to 12 Months After Anterior Cruciate Ligament Reconstruction.

Matthew S Harkey, Jeffrey B Driban, Shelby E Baez, Francesca M Genoese, Elaine Taylor Reiche, Katherine Collins, Michelle Walaszek, Ashley Triplett, Christopher Luke Wilcox, Andrew Schorfhaar and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of athletic training, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Matthew S HarkeyDepartment of Kinesiology, Michigan State University, East Lansing.
Jeffrey B DribanDepartment of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester.
Shelby E BaezUniversity of North Carolina at Chapel Hill.
Francesca M GenoeseDepartment of Kinesiology, Michigan State University, East Lansing.
Elaine Taylor ReicheUniversity of North Carolina at Chapel Hill.
Katherine CollinsUniversity of North Carolina at Chapel Hill.
Michelle WalaszekUniversity of Virginia, Charlottsville.
Ashley TriplettDepartment of Kinesiology, Michigan State University, East Lansing.
Christopher Luke WilcoxSparrow Sports Medicine, East Lansing, MI.
Andrew SchorfhaarSparrow Sports Medicine, East Lansing, MI.
Michael ShinglesSparrow Sports Medicine, East Lansing, MI.
Sheeba JosephMichigan State University Sports Medicine, East Lansing. Dr Genoese is now at the Division of Kinesiology and Health, University of Wyoming, Laramie.
Christopher KuenzeUniversity of Virginia, Charlottsville.
Michigan State University · USUniversity of North Carolina at Chapel Hill · USSparrow Hospital · USUniversity of Virginia · USSparrow Health System · USUniversity of Massachusetts Chan Medical School · USUniversity of Wyoming · US

Funding

Walk this Way: Physical Activity and Walking Biomechanics Lead to Early Knee OA Symptoms and Ultrasound-Detected Structural Pathology after ACL ReconstructionK01AR081389 · NIAMS · MICHIGAN STATE UNIVERSITY · PI Matthew Harkey · 2022 to 2026
$689k
NIAMS NIH HHS K01 AR081389
6 · The paper itself

Abstract

contextEarly identification of knee osteoarthritis (OA) symptoms after anterior cruciate ligament reconstruction (ACLR) could enable timely interventions to improve long-term outcomes. However, little is known about the change in early OA symptoms from 6 to 12 months post-ACLR.

objectiveTo evaluate the change over time in meeting classification criteria for early knee OA symptoms from 6 to 12 months after ACLR.

designProspective cohort study.

settingResearch laboratory. PATIENTS OR OTHER

participantsEighty-two participants aged 13 to 35 years who underwent unilateral primary ACLR. On average, participants' first and second visits were 6.2 and 12.1 months post-ACLR. MAIN OUTCOME MEASURE(S): Early OA symptoms were classified using generic (Luyten Original) and patient population-specific (Luyten Patient Acceptable Symptom State [PASS]) thresholds on Knee injury and Osteoarthritis Outcome Score (KOOS) subscales. Changes in meeting early OA criteria were compared between an initial and follow-up visit at an average of 6 and 12 months post-ACLR, respectively.

resultsTwenty-two percent of participants exhibited persistent early OA symptoms across both visits using both the Luyten Original and PASS criteria. From initial to follow-up visit, 18% to 27% had resolution of early OA symptoms, while 4% to 9% developed incident symptoms. In total, 48% to 51% had no early OA symptoms at either visit. No differences were found for change in early OA status between adults and adolescents.

conclusionsNearly one-quarter of participants exhibited persistent early knee OA symptoms based on KOOS thresholds from 6 to 12 months post-ACLR. Determining if this symptom persistence predicts worse long-term outcomes could inform the need for timely interventions after ACLR. Future researchers should examine if resolving persistent symptoms in this critical window improves later outcomes. Tracking early OA symptoms over time may identify high-risk patients who could benefit from early treatment.

Indexed as

Anterior Cruciate Ligament ReconstructionOsteoarthritis, KneeAdolescentAdultAnterior Cruciate Ligament InjuriesFemaleHumansMaleProspective StudiesTime FactorsYoung Adultknee injuryKOOSOA illnessposttraumaticPTOA

Identifiers

PMID38243733
PMCPMC11440826
OpenAlexW4391051950

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.